eoPred: Predicting the placental phenotype of early-onset preeclampsia using DNA methylation
I. Fernández-Boyano,
A.M. Inkster,
V. Yuan
et al.
Abstract:Background: A growing body of literature has reported molecular and histological changes in the human placenta in association with preeclampsia (PE). Placental DNA methylation (DNAme) and transcriptomic patterns have revealed molecular subgroups of PE that are associated with placental histopathology and clinical phenotypes of the disease. However, the heterogeneity of PE both across and within subtypes, whether defined clinically or molecularly, complicates the study of this disease. PE is most strongly assoc… Show more
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