volume 12, issue 5, P585-590 1978
DOI: 10.1002/jbm.820120502
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Abstract: We describe the preparation and some of the properties of heparin-bound alpha-chymotrypsin that were obtained via activation of heparin with water-soluble carbodiimide. Immobilized enzyme has unchanged kinetic characteristics toward low-molecular- weight and macromolecular substrates. The heparin-bound enzymes could have a wide range of medical applications.