Enzymatic Biosensors Based on Electrodeposited Alginate Hydrogels

One-step electrodeposited hybrid nanofilms in amperometric biosensor development

“…91 Electrodeposited alginate hydrogels have provided an appropriate environment for cell immobilization 92,93 and have shown promising results in biosensing applications. 94 ED is typically considered a simple strategy to produce various polymeric lms, with the advantages of temporal and spatial controllability. Electrochemical synthesis of polyanilines, polythiophenes and polypyrroles layers has been realized as a crucial approach for producing functional lms with controlled thickness and electrical conductivity.…”

A new method for early diagnosis of liver cancer using a biosensor embedded in an alginate polymer thin film

“…Accordingly, alginate based matrices have been used in biosensing applications to detect a wide range of molecules. [25][26][27][28][29] The high viscosity of the water soluble alginate solution enables different kinds of molecules to be embedded including organic and inorganic ones. The alginate has many advantages in the formulation of the biosensors.…”

Enzymes Encapsulated within Alginate Hydrogels: Bioelectrocatalysis and Electrochemiluminescence Applications

“…These materials are cross-linked hydrophilic polymers that adsorb high quantity of water and still retaining the structure, despite their considerable swelling. − The property of swelling is particularly useful in biomedical applications as this allows drugs to be transported inside the hydrogels and to be released selectively where it is required. , The gelation of alginate is generally achieved by exchanging the sodium ions from the guluronic acid of the polymer chain with the divalent cations Ca 2+ . − Hydrogel materials have also been used for various biotechnological applications like biosensing due to their biocompatibility, highly adaptable nature, and the significant property to swell in the presence of an aqueous environment. In particular, hydrogels based on natural polysaccharides have been employed for the development of enzymatic biosensors using different immobilization techniques . It is well known that hydrogels can be formulated in different ways including among others, microbeads.…”

“…In particular, hydrogels based on natural polysaccharides have been employed for the development of enzymatic biosensors using different immobilization techniques. 12 It is well known that hydrogels can be formulated in different ways including among others, microbeads. Fully biocompatible ionically cross-linked alginate hydrogels are very appealing as they offer the possibility to entrap active substances such as drugs and/or cells without affecting their biological activity.…”