Enterobacteriaceae Pseudomonas aeruginosa and Streptobacillus moniliformis

Holcombe, Hilda; Schauer, David B.

doi:10.1016/b978-012369454-6/50043-1

Cited by 3 publications

(5 citation statements)

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“…Descriptions of spontaneous severe C rodentium –associated colitis with significant mortality in adult mice are relatively rare, the majority of reports being of self–limited hyperproliferative responses of the colonic epithelium (reviewed in Holcombe and Schauer 15 ) that have been associated with activation of NF-κB and alterations in CKIε that influence β--catenin signaling. 29,32 Genetic background affects severity and outcome of natural and experimental infection, with C3H/HeJ mice being the most sensitive adult strain examined.…”

Section: Discussionmentioning

confidence: 99%

“…The severity of lesions varies with mouse strain and age, C57BL/6 being relatively resistant, and most infections resolve spontaneously. 15,19 This report describes the colonic lesions seen in MAIDS mice and their etiologic association with infection by C rodentium.…”

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confidence: 99%

“…2,15,25 Features of TMCH include rectal prolapse, diarrhea, and thickened, dilated colon, as well as a histologic picture of epithelial cell hyperplasia and crypt elongation. The severity of lesions varies with mouse strain and age, C57BL/6 being relatively resistant, and most infections resolve spontaneously.…”

mentioning

confidence: 99%

“…A naturally occurring disease of mice, transmissible murine colonic hyperplasia (TMCH), is caused by Citrobacter rodentium, formerly known as Citrobacter freundii biotype 4280. 2,15,25 Features of TMCH include rectal prolapse, diarrhea, and thickened, dilated colon, as well as a histologic picture of epithelial cell hyperplasia and crypt elongation. The severity of lesions varies with mouse strain and age, C57BL/6 being relatively resistant, and most infections resolve spontaneously.…”

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confidence: 99%

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Citrobacter-Induced Colitis in Mice With Murine Acquired Immunodeficiency Syndrome

2010

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Over the period of a year, colitis was observed in 44 mice raised in a conventional nonspecific pathogen–free colony, 41 of these having concomitant retrovirus–induced murine acquired immunodeficiency syndrome (MAIDS). The lesions varied from bacterial colonization to hyperplasia of colonic mucosa to severe, often fatal, ulceration. Citrobacter rodentium was isolated from the colon and/or liver of 2 mice with colitis. When C57BL/6 mice with or without MAIDS were given graded doses of the bacterium, only those with MAIDS developed colitis, and C rodentium was reisolated from their livers. Thus, mice with MAIDS can develop severe disease following opportunistic infection with an environmental contaminant of the colony that is nonpathogenic for normal adult mice.

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Section: Discussionmentioning

confidence: 99%

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Citrobacter-Induced Colitis in Mice With Murine Acquired Immunodeficiency Syndrome

2010

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“…Gram-negative bacteria of the Enterobacteriaceae family are important causes of urinary tract infections (UTIs), bloodstream infections, and various intra-abdominal infections (Paterson, 2006;Tan, 2008). Enterobacteriaceae are a large, heterogeneous family consists of 41 genera of Gram-negative, facultatively anaerobic bacteria (Holcombe and Schauer, 2007). Enterobacteriaceae often are labeled as 'enteric bacteria' because of their predilection for intestinal colonization.…”

Section: Introductionmentioning

confidence: 99%

Distribution of Multidrug-Resistant Gram-Negative Bacterial Infection in Hospitalized Infants

Mansour

Zaki

Abou‐Dobara

et al. 2010

Journal of Agricultural Chemistry and Biotechnology

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Sixty-five Gram-negative bacterial isolates were collected from different samples (blood, urine, stool, cerebrospinal fluid (CSF) and wound swabs) from Mansoura University Children's Hospital, and identified as Klebsiella pneumoniae (n= 10), Escherichia coli (n= 8), Enterobacter aerogenes (n= 7), Enterobacter cloacae (n= 6), Serratia fonticola (n= 6), Citrobacter freundii complex (n= 5), Kluyvera ascorbata (n= 4), Acinetobacter baumannii/haemolyticus (n= 3), Pseudomonas aeruginosa (n= 2), Pseudomonas fluorescens⁄putida (n= 2), Vibrio alginolyticus (n= 2), Vibrio damsela (n= 1), Cedecea lapagei (n= 1), Cedecea species 3 (n= 1), Proteus mirabilis (n= 1), Providencia stuartii (n= 1), Serratia marcescens (n= 1), Serratia plymuthica (n= 1), Serratia liquefaciens (n= 1), Stenotrophomonas maltophilia (n= 1) and Acinetobacter lwoffii (n= 1). Thirty-one antimicrobial agents were tested against the isolated bacteria. Gatifloxacin, imipenem and meropenem were found to be the most effective agents against the isolated bacteria, while ampicillin, cefotaxime, ceftazidime, ceftriaxone, cefuroxime, gentamicin and tobramycin were found to be of low effect against the isolated bacteria.

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