1949
DOI: 10.1001/archderm.1949.01530040125008
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Enhancing Photodynamic Effect of Solutions of Crude Coal Tar on the Skin

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Cited by 9 publications
(5 citation statements)
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“…The experiment with crude coal tar, however, was entirely negative. could not demonstrate photosensitization under the conditions recommended by Goeckerman (1925Goeckerman ( , 1931 for his treatment. The experiments of are supported by an Editorial Comment in the Yearbook of Derrnatology and Syphilology (1949).…”
mentioning
confidence: 76%
See 1 more Smart Citation
“…The experiment with crude coal tar, however, was entirely negative. could not demonstrate photosensitization under the conditions recommended by Goeckerman (1925Goeckerman ( , 1931 for his treatment. The experiments of are supported by an Editorial Comment in the Yearbook of Derrnatology and Syphilology (1949).…”
mentioning
confidence: 76%
“…Reviewing critically the literature on this subject, one must conclude that, although the good results of combined treatment, especially with tar and u.v. light, are nearly always ascribed, at least in part, to the favourable effect of the irradiation, no proof of this effect has been provided, since no comparisons were made with the effect of tar alone (Epstein, 1947;Goeckerman, 1925Goeckerman, , 1931Forck, 1966/67;MacKenna, 1959;Church, 1958).…”
Section: Discussionmentioning
confidence: 99%
“…Frank (16) showed a definite UV-light filter effect with various preparations of coal tar. He also found that the diffcrent solvents gave different photo sensitizing effects.…”
Section: Dlscussionmentioning
confidence: 98%
“…The coal tar extract used has a certain fight-filter effect (9,16). It, by itself, also has a certain healing effect on psoriasis.…”
Section: Dlscussionmentioning
confidence: 99%
“…Goeckerman (1931) certainly believed that coal tar photosensitized the skin, but a number of studies since then have cast doubt on the value of the ultraviolet component in the Goeckerman regimen, the coal tar by itself being just as effective in psoriasis (Ellis, Woolridge & Weiss, 1948;Young 1970aYoung , b, 1972. The conflicting views on this may result from quite simple differences in technique; Frank (1949) showed that solutions of coal tar when on the skin protected it against a carbon-arc u.v. erytheme dose (presumably by a direct screening effect), but enhanced the erythema if washed off before the u.v.…”
mentioning
confidence: 99%