Enhanced Recovery after Surgery Protocol (ERAS) combined with laparoscopic colorectal surgery diminishes the negative impact of sarcopenia on short-term outcomes

Abstract

management (CM). Reduction in the median length of hospitalisation was considered as primary outcome, incidence of perioperative complications and readmissions rates up to 28 days after surgery, and related costs differences were considered as secondary outcomes. The study began in June 2014, with an estimated enrollment of 100 patients over a period of 3 years and an intermediate analysis of the data at 1.5 years, the results of which we present in this paper. Results: From July 2014 to December 2015, 29 patients had been included, 13 in the ERAS group, and 16 in the CM Group. Epidemiological characteristic, surgery indication, stage at diagnosis and surgical procedures were similar in both groups with no statistically significant differences. In the ERAS group compliance with ERAS protocol was >90% for all the items except for avoidance of abdominal drainage (47%). Median length of hospitalisation was 9 days for CM group and 7 days for the ERAS group (p¼0.09), with apparent but not statistically significant differences between complication (86% vs. 53% p¼0.12) and readmission rates (37% vs. 15% p¼0.24). Conclusion: In the PROFAST intermediate analysis, ERAS appeared to be a safe measure, with the potential of significantly reduce the median length of hospitalisation and patient related costs in advanced ovarian cancer surgery. Disclosure of interest: None declared.

Low skeletal muscle mass and postoperative morbidity in surgical oncology: a systematic review and meta‐analysis

“…9,10 Both a negative and a positive effect of the presence of sarcopenia on the development of severe complications have been reported. [11][12][13][14][15][16][17][18] Therefore, we performed a systematic review and meta-analysis of all the studies that recorded incidences of severe postoperative complications in patients with or without sarcopenia, undergoing oncological surgery for any type of solid tumour.…”

“…Amini, 201524 Banaste, 201716 Chemama, 201625 Choi, 201826 Coelen, 201527 Elliot, 201728 Grotenhuis, 201629 Harada, 201530 Harimoto, 201331 Higashi, 201532 Jarvinen, 201833 Jones, 201534 Kudou, 201735 Kuwada, 201836 Levolger, 201537 Lodewick, 201538 Malietzis, 201639 Mason, 201740 Mayr, 201841 Nakamura, 201842 Nakashima, 201843 Nakanishi, 201844 Nimomiya, 201745 Nishida, 201646 Nishigori, 201647 Okumura, 201648 Okumura, 2015a49 Okumura, 2015b50 Otsuji, 201551 Ouchi, 201652 Pędziwiatr, 201618 Peng, 201153 Peyton, 201654 (Continues)…”

Asociación entre desenlaces clínicos y cumplimiento del protocolo de recuperación mejorada después de la cirugía (ERAS) en procedimientos colorrectales: estudio multicéntrico

“…Hasta el momento, la mayoría de los estudios sobre protocolos ERAS y desenlaces en cirugía colorrectal se han centrado en evaluar y comparar el nivel de adherencia al protocolo con resultados como la duración de la estancia hospitalaria posquirúrgica relacionada con el procedimiento principal y frecuencia de complicaciones. Este estudio muestra el análisis de la implementación en instituciones de Latinoamérica y los resultados en cirugía de colon y recto fueron consistentes con los hallazgos positivos reportados en instituciones de países desarrollados 13,31,[41][42][43][44] .…”