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Cited by 7 publications
(8 citation statements)
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“…Although RH40: GEL +10% αCD caused lower accumulation of TB in the most external layers, a higher amount of TB was quantified after 72 and 144 h ( Fig. 10 b), which indicated TB penetration in the innermost regions of the hooves ( Krawczyk-Santos et al, 2021 ; Rocha et al, 2017 ). The amount of drug extracted (72 and 144 h) was about two times greater for RH40: GEL +10% αCD compared to all other formulations (p < 0.05).…”
Section: Resultsmentioning
confidence: 95%
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“…Although RH40: GEL +10% αCD caused lower accumulation of TB in the most external layers, a higher amount of TB was quantified after 72 and 144 h ( Fig. 10 b), which indicated TB penetration in the innermost regions of the hooves ( Krawczyk-Santos et al, 2021 ; Rocha et al, 2017 ). The amount of drug extracted (72 and 144 h) was about two times greater for RH40: GEL +10% αCD compared to all other formulations (p < 0.05).…”
Section: Resultsmentioning
confidence: 95%
“…When the nail plate absorbs water, pores can increase in number and size, an expansion of the structure occurs, increasing the porosity of the previously compact internal area. Hydrated nails also become more elastic, facilitating the permeation of different molecules ( Chouhan and Saini, 2012 ; Cutrin-Gomez et al, 2018c ; Gunt et al, 2007 ; Krawczyk-Santos et al, 2021 ; Nogueiras-Nieto et al, 2011 ). The effects of the formulations on the nail plate were quantified by means of the hydration enhancement factor (HEF24) ( Fig.…”
Section: Resultsmentioning
confidence: 99%
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“…A permeation enhancement pre-treatment of the nail plates was performed as a modification of previously demonstrated treatments [ 47 , 48 ]. An aqueous solution of 10% w / v TGA and 10% w / v PEG 400 was used for the pre-treatment of the nails, achieved by overnight incubation of the nail plates.…”
Section: Methodsmentioning
confidence: 99%