Enhanced Blood Conservation in Primary Coronary Artery Bypass Surgery Using Heparin-Bonded Circuits with Lower Anticoagulation

Aldea, Gabriel S.; Zhang, Xi; Memmolo, Ciriaco A.; Shapira, Oz M.; Treanor, Patrick R.; Kupferschmid, John P.; Lazar, Harold L.; Shemin, Richard J.

doi:10.1111/j.1540-8191.1996.tb00018.x

Cited by 12 publications

(2 citation statements)

References 30 publications

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“…Several methods have been proposed in an attempt to minimize the blood loss in heart surgery, including the use of cell savers [5], autotransfusions [6], heparin-lined circuits [7], leukocyte filters [8] and antifibrinolytic drugs [9]. The inconvenience of these methods is in the high cost required to routinely implement them.…”

Section: Introductionmentioning

confidence: 99%

Fatores de risco de sangramento no pós-operatório de cirurgia cardíaca em pacientes adultos

Miana¹,

Atik²,

Moreira³

et al. 2004

Rev Bras Cir Cardiovasc

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Objective: To determine predictors of postoperative bleeding after cardiac surgery, in order to focus on preventive measures for high-risk populations.Methods: From October 2001 to March 2002, 411 consecutive adult cardiac surgery patients were prospectively studied, with the exception of those submitted to heart transplantation. In order to determine risk factors for postoperative bleeding, 20 preoperative, 17 operative and 6 postoperative variables were analyzed using univariate methods and multiple linear regression.Results: Operative procedures included coronary artery bypass grafting in 227 (55.2%) patients, valvar operations in 198 (48.2%), aortic surgery in 25 (6.1%) and combined procedures in 60 (14.6%). Cardiopulmonary bypass was used in 335 (81.5%) patients and anti-fibrinolysis agents in 148 (36%). The thirty-day mortality rate was 5.6% (23 patients). Mean 24-hour postoperative blood loss was 610 ± 500 mL (range 10-4900). Re-exploration for bleeding was required in 15 (3.7%) patients. Independent predictors of postoperative bleeding were emergency operations (p=0.049), postoperative metabolic acidosis (p=0.001), preoperative thrombocytopenia (p=0.034) and prolonged cardiopulmonary bypass (p=0.021).Conclusions: When possible, preoperative stabilization and correction of coagulation disturbances should be achieved in patients requiring urgent or emergent surgery and in those with thrombocytopenia. The duration of cardiopulmonary bypass should be minimized as long as this is practical. Postoperative metabolic acidosis must be actively corrected, especially the main determining causes. Descriptors

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Section: Introductionmentioning

confidence: 99%

Fatores de risco de sangramento no pós-operatório de cirurgia cardíaca em pacientes adultos

Miana¹,

Atik²,

Moreira³

et al. 2004

Rev Bras Cir Cardiovasc

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show abstract

“…The methods proposed to minimize blood loss in cardiac surgery include the use of cell saver 3 , autotransfusion 4 , heparin-bonded circuits 5 , leukocyte filters 6 , and antifibrinolytic drugs 7 . The disadvantages of these methods reside in their elevated costs for routine, wide implementation.…”

mentioning

confidence: 99%

A cirurgia de revascularização do miocárdio sem circulação extracorpórea minimiza o sangramento pós-operatório e a necessidade transfusional

Atik¹,

Miana²,

Jatene³

et al. 2004

Arq. Bras. Cardiol.

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Extracorporeal Devices and Related Technologies

Groom¹,

Stammers²

2011

Kaplan's Cardiac Anesthesia: The Echo Era

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Enhanced Blood Conservation in Primary Coronary Artery Bypass Surgery Using Heparin-Bonded Circuits with Lower Anticoagulation

Abstract: In summary, HBCs in conjunction with lower anticoagulation were safely applied in patients undergoing primary CABG with marked improvement in blood conservation, and should be considered for broader clinical use.

Cited by 12 publications

References 30 publications

Fatores de risco de sangramento no pós-operatório de cirurgia cardíaca em pacientes adultos

Fatores de risco de sangramento no pós-operatório de cirurgia cardíaca em pacientes adultos

A cirurgia de revascularização do miocárdio sem circulação extracorpórea minimiza o sangramento pós-operatório e a necessidade transfusional

Extracorporeal Devices and Related Technologies

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