Enfermedad de Behçet asociada a déficit de corticotropina

P, Sánchez Sobrino; Fernández, Concepción Páramo; Ferreiro, José Luis; Gil, Beatriz; R, Palmeiro Carballeira; Rv, García-Mayor

doi:10.1016/s1575-0922(09)72968-7

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…A case report by Sánchez Sobrino et al, from Spain reports a longstanding Behcet's patient developing adrenal insufficiency, caused by isolated corticotropin deficiency. In this sense they reviewed the literature for the possible mechanisms of hypothalamic-pituitary injury in BD [19]. …”

Section: Behcet's Disease and Adrenal Glandsmentioning

confidence: 99%

Behcet's Disease and Endocrine System

Özhan

Sezer

2012

Pathology Research International

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Behcet's disease (BD) is a chronic disease which is characterized by recurrent oral apthous ulcerations, recurrent genital ulcerations, skin eruptions, ocular involvements and other various systemic manifestations as well as systemic vasculitis. Endocrine involvement in BD regarding various systems can be seen. Hypophysis is one of the best and dense vascularized organs of the body, thus it is likely that it can be affected by BD. Not only anterior hypophysis functions, but posterior hypophysis functions as well can be affected. As BD is a disease of autoimmune process, it may be possible that adrenal insufficiency or alterations in the cortisol levels could be expected. Another concern is whether or not there is insulin resistance in patients with BD. The avaliable data suggests that there is an increased susceptibility to insulin resistance in patients with BD.

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Section: Behcet's Disease and Adrenal Glandsmentioning

confidence: 99%

Behcet's Disease and Endocrine System

Özhan

Sezer

2012

Pathology Research International

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Pathophysiology of the Behçet's Disease

Türsen

2012

Pathology Research International

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Behçet's disease (BD) is a multisystemic disease of unknown etiology characterized by chronic relapsing oral-genital ulcers and uveitis. Multiple systemic associations including articular, gastrointestinal, cardiopulmonary, neurologic, and vascular involvement are also observed in BD. Although the etiopathogenesis of the disease remains unknown, increased neutrophil functions such as chemotaxis, phagocytosis, and excessive production of reactive oxygen species (ROS), including superoxide anion, which may be responsible for oxidative tissue damage seen in BD, and also immunological alterations, T lymphocyte abnormalities in both subpopulation and function have been considered to be correlated with the etiopathogenesis of BD. There is some clinical evidence suggesting that emotional stress and hormonal alterations can influence the course and disease activity of BD.

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Enfermedad de Behçet asociada a déficit de corticotropina

Cited by 2 publications

References 27 publications

Behcet's Disease and Endocrine System

Behcet's Disease and Endocrine System

Pathophysiology of the Behçet's Disease

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