2018
DOI: 10.1097/scs.0000000000004175 View full text |Buy / Rent full text
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Abstract: Repair of leaks at lateral sphenoid sinus and posterior frontal sinus could achieve favorable results via selected endoscopic approaches. The failure of repair was associated with inaccessible leak sites, spontaneous leaks, raised ICP, and elevated BMI.

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“…Such finding strongly agrees with the literature that reports as early recurrences were mostly at the same repair site, whereas late recurrences are observed more frequently at distant site along the skull base; this may in fact represent a secondary leak rather than failure of the primary repair. 2 Although some authors proposed a preventive treatment in order to avoid the risk of development elevated ICP after reconstruction, 3 no clinical or radiological signs of intracranial hypertension were detected in the present population, even after a long-term follow-up.…”
Section: Discussionmentioning
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“…Such finding strongly agrees with the literature that reports as early recurrences were mostly at the same repair site, whereas late recurrences are observed more frequently at distant site along the skull base; this may in fact represent a secondary leak rather than failure of the primary repair. 2 Although some authors proposed a preventive treatment in order to avoid the risk of development elevated ICP after reconstruction, 3 no clinical or radiological signs of intracranial hypertension were detected in the present population, even after a long-term follow-up.…”
Section: Discussionmentioning
“…11 Song et al retrospectively analyzed 144 patients with CSFL, observing more multiple skull base defects in the sCSF group. 3 Similarly, Englhard et al retrospectively analyzed their experience in sCSF management, reporting up to 16.7% of multiple CSFL located in the ethmoidal roof. 1 Conversely, only 1 case of multiple CSFL was reported in our study population.…”
Section: Discussionmentioning
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“…Although in our study this represents only 2 of 20 cases due to our low N, this is consistent with previous studies linking increased BMI to higher failure rates of primary repair in all etiologies of CSF leaks. [37][38][39]…”
Section: Discussionmentioning
“…In this respect, our results are in line with the literature. However, it has to be kept in mind that the collective at hand is a relatively small one; recurrence rates of up to 25% and over a period of several months have been reported [ 33 ]. Therefore, there should be regular and long-term follow-up to detect recurrences early and avoid complications.…”
Section: Discussionmentioning