“…A meta-analysis has shown that the incidence of PEP in patients who underwent precut sphincterotomy was 5.28%, compared with 3.10% ( p < 0.001) in patients who did not [ 24 , 36 ]. Several studies have reported that the incidence of PEP was 5.5–21% [ 55 , 56 , 57 ] in TPS alone and 3.5–4.1% [ 50 , 58 , 59 , 60 ] in prophylactic PD stent placement after TPS. Moreover, the most recent studies have demonstrated that prophylactic PD stenting reduced the incidence of PEP [ 28 , 60 , 61 , 62 , 63 , 64 ].…”