Endogenous stimuli-responsive drug delivery nanoplatforms for kidney disease therapy

Ti3C2 MXene Nanosheet-Based Dual-Enzyme Cascade Reaction to Facilitate Dual-Stimulation-Mediated Breast Cancer Therapy

“…Unlike the normal tissue environment, the tumor microenvironment (TME) provides a suitable environment for tumor cell survival, division, angiogenesis, and metastasis. , The tissue environment manifests itself in various aspects of specificity, such as tissue structure, tissue nutritional status, pH and O 2 levels, chronic inflammatory state, etc., all of which are prerequisites for promoting tumor growth . In response to these variability studies, it was found that changes in the concentration of some molecules during the catalytic process of TME cause endogenous stimulation of biological systems, such as glucose, acidic pH, and some specific enzymes. ,− By altering these molecular concentrations, we can generate a variety of anticancer regimens that arise from endogenous stimuli.…”