Endocrine Review: THE CLINICAL SIGNIFICANCE OF THE BLOOD IODINE: A REVIEW*

The Concentration and Significance of the Butanol-Extractable I131 of Serum in Patients with Diverse States of Thyroidal Function

“…The concentration of hormonal iodine in the plasma of hyperthyroid patients is greater than normal (20,21). Nevertheless, in such patients following a tracer dose of 1181, the S.A. of the PBI increases more rapidly than normal (22).…”

The Concentration and Significance of the Butanol-Extractable I131 of Serum in Patients with Diverse States of Thyroidal Function

“…The concentration of hormonal iodine in the plasma of hyperthyroid patients is greater than normal (20,21). Nevertheless, in such patients following a tracer dose of 1181, the S.A. of the PBI increases more rapidly than normal (22).…”

The Clinical Determination of Protein-Bound Iodine 1

“…The value of plasma protein-bound iodine (PBI) measurement in the evaluation of thyroid disease has been well established (1)(2)(3)(4)(5)(6)(7), but it has not yet assumed its deserved place in the clinical armamentarium because of the technical difficulties involved in distillation procedures. Modification of an alkaline-incineration technique (8) has resulted in the evolution of a method for PBI determination which is practicable for a clinical laboratory.…”

“…The blood sample may be collected with an anticoagulant or may be allowed to clot. The advantages of the former are speed in obtaining the plasma and a larger volume of fluid resulting, and of the latter that no foreign material need be added 3 Obtainable from the Finger Lakes Chemical Co., Etna, N. Y.…”

The Concentration and Significance of the Butanol-Extractable I131 of Serum in Patients with Diverse States of Thyroidal Function

“…The concentration of hormonal iodine in the plasma of hyperthyroid patients is greater than normal (20,21). Nevertheless, in such patients following a tracer dose of 1181, the S.A. of the PBI increases more rapidly than normal (22).…”

The Clinical Determination of Protein-Bound Iodine 1

“…The value of plasma protein-bound iodine (PBI) measurement in the evaluation of thyroid disease has been well established (1)(2)(3)(4)(5)(6)(7), but it has not yet assumed its deserved place in the clinical armamentarium because of the technical difficulties involved in distillation procedures. Modification of an alkaline-incineration technique (8) has resulted in the evolution of a method for PBI determination which is practicable for a clinical laboratory.…”

“…The blood sample may be collected with an anticoagulant or may be allowed to clot. The advantages of the former are speed in obtaining the plasma and a larger volume of fluid resulting, and of the latter that no foreign material need be added 3 Obtainable from the Finger Lakes Chemical Co., Etna, N. Y.…”

The Concentration and Significance of the Butanol-Extractable I131 of Serum in Patients with Diverse States of Thyroidal Function

“…The concentration of hormonal iodine in the plasma of hyperthyroid patients is greater than normal (20,21). Nevertheless, in such patients following a tracer dose of 1181, the S.A. of the PBI increases more rapidly than normal (22).…”

The Clinical Determination of Protein-Bound Iodine 1

“…The value of plasma protein-bound iodine (PBI) measurement in the evaluation of thyroid disease has been well established (1)(2)(3)(4)(5)(6)(7), but it has not yet assumed its deserved place in the clinical armamentarium because of the technical difficulties involved in distillation procedures. Modification of an alkaline-incineration technique (8) has resulted in the evolution of a method for PBI determination which is practicable for a clinical laboratory.…”

“…The blood sample may be collected with an anticoagulant or may be allowed to clot. The advantages of the former are speed in obtaining the plasma and a larger volume of fluid resulting, and of the latter that no foreign material need be added 3 Obtainable from the Finger Lakes Chemical Co., Etna, N. Y.…”