Encoding Enantiomeric Molecular Chiralities on Graphene Basal Planes

Abstract

Graphene has demonstrated broad applications due to its prominent properties. Its molecular structure makes graphene achiral. Here, we propose a direct way to prepare chiral graphene by transferring chiral structural conformation from chiral conjugated amino acids onto graphene basal plane through π–π interaction followed by thermal fusion. Using atomic resolution transmission electron microscopy, we estimated an areal coverage of the molecular imprints (chiral regions) up to 64 % on the basal plane of graphene (grown by chemical vapor deposition). The high concentration of molecular imprints in their single layer points to a close packing of the deposited amino acid molecules prior to “thermal fusion”. Such “molecular chirality‐encoded graphene” was tested as an electrode in electrochemical enantioselective recognition. The chirality‐encoded graphene might find use for other chirality‐related studies and the encoding procedure might be extended to other two‐dimensional materials.

Stereospecific Self-Assembly Processes of Porphyrin-Proline Conjugates: From the Effect of Structural Features and Bulk Solvent Properties to the Application in Stereoselective Sensor Systems

“…The implementation of elements of chirality, for example, in GO derivatives would represent a fine tuning of the above-described properties for the stereoselective detection and removal of chiral noxious wastes. The chiral functionalisation of GO surfaces has been reported, mainly through bonds with amino acid derivatives [ 93 , 94 , 95 ]. Although both non-covalent and covalent porphyrin-GO conjugates are widely reported [ 96 ], mostly for photovoltaic [ 97 ] or cancer treatment [ 98 , 99 , 100 , 101 ], none of which involve strictu sensu chiral porphyrins, except for the presence of a coordinated chiral group to the central metal ion [ 102 , 103 ].…”

Chiral nanomaterial-based approaches for diagnosis and treatment of protein-aggregated neurodiseases: current status and future opportunities

“…84–86 Since chiral nanomaterials can have highly specific chiral interaction with their corresponding stereoisomer counterparts just like the “key-lock” concept, suggesting that some indirect measurements based on the finding of the binding energy using isothermal calorimetry (ITC) and chiral-specific interactions using fluorescence spectroscopy can also be used for determining chirality. 20,87 Although CD spectroscopy is still a very important technique to measure chirality, recent innovations have shown that some other techniques can also give excellent results. Moreover, by combining different techniques, more detailed structural and morphological information associated with chiral nanomaterials can easily be extracted.…”

N-Doped Porous Graphitic Carbon Hybridized with CrN Nanocrystals: Electrocatalysis-Induced Li2S Three-Dimensional Growth and Enhanced Cathode Kinetics

“…To date, TMNs derived from the transition metals in the fourth row, for instance, TiN, VN, CrN, Mn 3 N 2 , Fe 2 N, Co 4 N, Ni 3 N, and Cu 3 N, have been mostly studied. These TMNs exhibit exceptional ionic and electronic conductivities when used in electrochemical energy storage devices (e.g., Li-ion batteries , or supercapacitors − ) as well as outstanding electrocatalytic activities when used to facilitate electrochemical energy conversion chemistry (e.g., the hydrogen evolution, , oxygen evolution, , and oxygen reduction reactions − ). In general, TMNs have been prepared using two methods .…”