Enantiomeric separations in capillary zone electrophoresis using a chiral crown ether

Chiral separation by chromatographic and electromigration techniques. A Review

“…18C6H4 was used in combination with CDs [468,469]. It was shown that not only chiral but also non-chiral crown ethers can support chiral recognition of CDs [470].…”

Chiral Analyses of Pollutants by Capillary Electrophoresis

“…The carboxylic groups of crown ether; perpendicular to the plane of the ring; form a chiral barrier which divides the space available for the substituents at the chiral centre of the enantiomers into two domains. In this way, two different diastereoisomeric complexes are formed which separated onto CE [40]. Kuhn et al [41] proposed the chiral recognition mechanism based on space availability for the substutents of both the chiral carbon atoms; adjacent to amine functional groups; into two cavities.…”

Development of Advanced Capillary Electrophoresis Techniques with UV and Mass Spectrometry Detection for Forensic, Pharmaceutical and Environmental Applications

“…It is possible to use other chiral selectors as alternative ways to fulfill the goal of enantioseparation using CE with UV and MS detection. Several chiral selectors have been reported for chiral separations, including antibiotics [128,132,213,214], crown ether [121,124,126,215,216], and other compounds [217,218]. However, it should be noted that among various chiral …”

“…In this project presented in Chapter 3, the capability of CE has been investigated in the determination of synthetic cathinone analogs. With CE, numbers of chiral selectors are available for use, including crown ether [117][118][119][120][121][122][123][124][125][126][127] and antibiotics [128][129][130][131][132][133][134][135]. Among them, cyclodextrins (CDs) and their analogs are the most commonly used [107,136].…”