Emprego experimental da placa de compósito poli-hidroxibutirado/hidroxiapatita na fixação femoral em gatos

Alves, Endrigo Gabellini Leonel; Rezende, C.M.F.; Oliveira, H.P.; Borges, Natalie Ferreira; Mantovani, Plinio Ferreira; Rosado, Isabel Rodrigues

doi:10.1590/s0102-09352010000500015

Cited by 8 publications

(9 citation statements)

References 15 publications

(5 reference statements)

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“…In this application the product may be subjected to body fluids and mechanical loads that might cause ESC. For example, when using PHB implants in cats, failure was reported at very low levels of stresses 20 , but the relation to ESC was not considered by the authors.…”

Section: Introductionmentioning

confidence: 99%

Environmental Stress Cracking of Poly(3-hydroxibutyrate) Under Contact with Sodium Hydroxide

et al. 2015

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Environmental stress cracking (ESC) is one of the most important causes of polymer premature failure, occurring when a combination of mechanical load and an aggressive fluid is applied. The phenomenon is well know by polymer producers and product designers but its mechanisms are not very well understood. Although the ESC effects of many commercial polymers are well known, this type of failure in biopolymers were not studied yet. In the current work, the stress cracking behaviour of poly(3-hydroxybutyrate) (PHB) with 4,0 and 6,2% of hydroxyvalerate (HV) was investigated in injection-moulded bars under contact with sodium hydroxide (NaOH) solutions. The experiments were conducted using two different types of stress arrangements: (i) an ordinary tensile testing and (ii) a relaxation experiment. In both situations the injection-moulded bars were exposed to the NaOH solution and some testing conditions where varied, like the cross-head speed of the tensile test and the maximum load of the relaxation arrangement. The results showed that NaOH acted as a strong stress cracking agent for PHB, causing surface cracking and reducing significantly the mechanical properties. Catastrophic failure with an extensive surface damage was also observed by photographed and scanning electron microscopy (SEM) images. The magnitude of the effects increased with decreasing crosshead speed and increasing loading level.

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Section: Introductionmentioning

confidence: 99%

Environmental Stress Cracking of Poly(3-hydroxibutyrate) Under Contact with Sodium Hydroxide

et al. 2015

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“…Para uso na reparação de falhas ósseas, os implantes têm que ser esterilizados, e as melhores opções são com o uso de radiação gama e óxido de etileno (Alves et al 2010). Além, desses dois métodos, a esterilização também pode ser realizada com o uso de autoclave, que foi a técnica utilizada neste estudo para esterilizar os corpos de prova , Moreira et al 2014.…”

Section: Resultsunclassified

“…Para isso, torna-se necessário a realização de ensaios mecânicos específicos, que depende do tipo de material a ser testado, da finalidade a que se destina, do tipo de esforço ao qual será submetido e, também, das propriedades do biomaterial (França et al 2008, Singh et al 2013, Ueno et al 2015. Como o esqueleto apendicular dos animais está sob ação de um conjunto de forças, dentre elas a de compressão, o teste mecânico de compressão axial, atualmente, é o mais utilizado para avaliar a resistência mecânica de biomaterial, principalmente os cilíndricos (Amendola et al 2008, Alves et al 2010, Sonagli et al 2011.…”

Section: Resultsunclassified

Estudo comparativo da resistência mecânica da força de compressão entre biomateriais naturais, sintéticos e mistos

et al. 2017

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“…The methylmethacrylate has bioinert and biotolerable properties, can be molded to obtain a more adequate form, therefore is currently widely used in orthopedic surgical procedures to repair large bone defects 2,12,18 .…”

Section: Introductionmentioning

confidence: 99%

Tomographic imaging of fragmented cortical bone heteroimplant and methylmethacrylate in segmental bone defect of rabbit tibia

et al. 2014

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PURPOSE:To evaluate the performance of composites consisting of fragmented cortical bone heteroimplant in association with methylmethacrylate preserved in 98% glycerin, in segmental bone defect of rabbit tibia medial metaphysis. METHODS:In this study were used twelve adult New Zealand rabbits, divided into three groups of four animals each: G30 (30 days), G60 (60 days) and G90 (90 days). The bone defects previously created in the tibia were filled with composites and both were evaluated by cone-beam computed tomography, immediately after surgery and after 30, 60, and 90 days. RESULTS:The composites fulfilled and remained in the sites of bone defects in all cases and were not registered signals of infection, migration or rejection. CONCLUSIONS:The implanted composites promoted the bone defects repair without signals of infection and/or rejection. The composites are one more option for bone defects repair.

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Emprego experimental da placa de compósito poli-hidroxibutirado/hidroxiapatita na fixação femoral em gatos

Cited by 8 publications

References 15 publications

Environmental Stress Cracking of Poly(3-hydroxibutyrate) Under Contact with Sodium Hydroxide

Environmental Stress Cracking of Poly(3-hydroxibutyrate) Under Contact with Sodium Hydroxide

Estudo comparativo da resistência mecânica da força de compressão entre biomateriais naturais, sintéticos e mistos

Tomographic imaging of fragmented cortical bone heteroimplant and methylmethacrylate in segmental bone defect of rabbit tibia

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