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Cited by 339 publications
(342 citation statements)
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References 30 publications
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“…Treatment with swallowed topical corticosteroids was shown to be protective against food impaction in this group (OR 0.411, 95% CI: 0.203-0.835, P = 0.014) [91]. Regarding efficacy of food elimination in maintenance therapy, a study by Lucendo et al found that patients who continued to avoid offending foods in an elimination diet were found to maintain histopathologic and clinical EoE remission for up to 3 years [92]. Current guidelines recommend considering long-term topical steroids and /or dietary restriction in all patients, especially patients with severe dysphagia, food impaction, esophageal stricture, and rapid symptomatic / histologic relapse following initial therapy [4].…”
Section: Maintenance Of Therapymentioning
confidence: 83%
“…Treatment with swallowed topical corticosteroids was shown to be protective against food impaction in this group (OR 0.411, 95% CI: 0.203-0.835, P = 0.014) [91]. Regarding efficacy of food elimination in maintenance therapy, a study by Lucendo et al found that patients who continued to avoid offending foods in an elimination diet were found to maintain histopathologic and clinical EoE remission for up to 3 years [92]. Current guidelines recommend considering long-term topical steroids and /or dietary restriction in all patients, especially patients with severe dysphagia, food impaction, esophageal stricture, and rapid symptomatic / histologic relapse following initial therapy [4].…”
Section: Maintenance Of Therapymentioning
confidence: 83%
“…Among studies that examined the effectiveness of monoclonal antibody treatment in EoE subjects, 80% defined histological remission as peak esophageal eosinophil counts within the range of 0 to ≤5 24, 25, 26, 27, 28. Approximately 26% (N = 15) of the eligible studies examined remission among EoE patients who received only the diet elimination treatment formula (SFED, FFGED, ELED) compared to other forms of treatment, with the most common definitions falling within 0 to ≤5 eosinophils/hpf 29, 30, 31, 32, 33, 34 or 11 to ≤15 eosinophils/hpf 35, 36, 37, 38, 39, 40. Interestingly, even among the SFED studies (N = 9), five studies defined remission within the range of 0 to ≤5 eosinophils/hpf, 29, 30, 31, 32, 34 and two studies considered histological remission as <15 eosinophils/hpf 38, 41…”
Section: Resultsmentioning
confidence: 99%
“…Of the 22 studies selected from European centers, 12 studies (55%) considered values within the range 11 to ≤15 eosinophils/hpf 17, 36, 37, 38, 39, 46, 47, 53, 54, 55, 56, 57, 58 as histological remission, and 4 studies (23%) defined histological remission as less than 5 or ≤ 5 eosinophils/hpf 30, 33, 42, 45. Strikingly, all studies conducted in Switzerland used a more stringent and consistent end‐point of <5 eosinophils /hpf to identify cases of histological remission 28, 59, 60…”
Section: Resultsmentioning
confidence: 99%
“…The six food elimination diet (SFED) is where six most common food allergens (wheat, egg, milk, soy, nuts and seafood) are initially excluded from the diet and then subsequently reintroduced in a stepwise fashion to assess any causative triggers. SFED is of proven efficacy for adults with EoE for both improving symptoms and reducing eosinophil counts [65,66] . The disadvantage of the SFED diet is that it may be difficult to follow.…”
Section: M P O R T a N C E O F D I A G N O S I S A N D Treatmentmentioning
confidence: 99%