EMLA and Amethocaine for reduction of children's pain associated with needle insertion

Abstract

Lander JA, Weltman BJ, So SS. EMLA and Amethocaine for reduction of children's pain associated with needle insertion.

Does topical Amethocaine cream increase first-time successful cannulation in children compared with a eutectic mixture of local anaesthetics (EMLA) cream? A systematic review and meta-analysis of randomised controlled trials

“…A previous review found Amethocaine to be superior to EMLA in pain control 5. A key difference between the study by Lander et al and the present review lies in the severity of the children's conditions.…”

“…However, considering our results in combination with the analgesic effects of Amethocaine5 and its potential cost-savings,17 a weak recommendation can be issued for the use of Amethocaine cream in the paediatric cannulation.…”

Does topical Amethocaine cream increase first-time successful cannulation in children compared with a eutectic mixture of local anaesthetics (EMLA) cream? A systematic review and meta-analysis of randomised controlled trials

“…A previous review found Amethocaine to be superior to EMLA in pain control 5. A key difference between the study by Lander et al and the present review lies in the severity of the children's conditions.…”

“…However, considering our results in combination with the analgesic effects of Amethocaine5 and its potential cost-savings,17 a weak recommendation can be issued for the use of Amethocaine cream in the paediatric cannulation.…”

Rehydration strategies in infants and children with acute gastroenteritis refusing or not tolerating an oral fluid challenge

“…In support of this, 34 out of 56 (61%) nurses also felt that NG tube insertion was more distressing for a child than IV cannulation 12. It is unclear if proven adjuncts for patient comfort such as topical local anaesthetic preparations13 and cold sprays14 were employed to facilitate the comfortable insertion of IV cannulae in this study.…”

Lidocaine spray vs mepivacaine local infiltration for suturing 1st/2nd grade perineal lacerations: a randomised controlled non-inferiority trial

“…Furthermore, compared to the infiltration of local anesthetic, there is a lower risk of bleeding [8,9]. The efficacy of non-injective local anesthetics for minor surgical procedures has already been demonstrated in various fields, both in the obstetric-gynecological and other disciplines [8,[23][24][25][26][27][28]. In particular, as regards the gynecological procedures, the studies have focused on the effects of various topical anesthetics in the puerperium, of EMLA during suturing of perineal lacerations, of lidocaine spray as anesthetic therapy in the second stage of labor or other gynecological procedures, such as colposcopy, outpatient hysteroscopy, and endometrial biopsies.…”

Does topical Amethocaine cream increase first-time successful cannulation in children compared with a eutectic mixture of local anaesthetics (EMLA) cream? A systematic review and meta-analysis of randomised controlled trials

“…A previous review found Amethocaine to be superior to EMLA in pain control 5. A key difference between the study by Lander et al and the present review lies in the severity of the children's conditions.…”

“…However, considering our results in combination with the analgesic effects of Amethocaine5 and its potential cost-savings,17 a weak recommendation can be issued for the use of Amethocaine cream in the paediatric cannulation.…”

Rehydration strategies in infants and children with acute gastroenteritis refusing or not tolerating an oral fluid challenge

“…In support of this, 34 out of 56 (61%) nurses also felt that NG tube insertion was more distressing for a child than IV cannulation 12. It is unclear if proven adjuncts for patient comfort such as topical local anaesthetic preparations13 and cold sprays14 were employed to facilitate the comfortable insertion of IV cannulae in this study.…”

Lidocaine spray vs mepivacaine local infiltration for suturing 1st/2nd grade perineal lacerations: a randomised controlled non-inferiority trial

“…Furthermore, compared to the infiltration of local anesthetic, there is a lower risk of bleeding [8,9]. The efficacy of non-injective local anesthetics for minor surgical procedures has already been demonstrated in various fields, both in the obstetric-gynecological and other disciplines [8,[23][24][25][26][27][28]. In particular, as regards the gynecological procedures, the studies have focused on the effects of various topical anesthetics in the puerperium, of EMLA during suturing of perineal lacerations, of lidocaine spray as anesthetic therapy in the second stage of labor or other gynecological procedures, such as colposcopy, outpatient hysteroscopy, and endometrial biopsies.…”

Does topical Amethocaine cream increase first-time successful cannulation in children compared with a eutectic mixture of local anaesthetics (EMLA) cream? A systematic review and meta-analysis of randomised controlled trials

“…A previous review found Amethocaine to be superior to EMLA in pain control 5. A key difference between the study by Lander et al and the present review lies in the severity of the children's conditions.…”

“…However, considering our results in combination with the analgesic effects of Amethocaine5 and its potential cost-savings,17 a weak recommendation can be issued for the use of Amethocaine cream in the paediatric cannulation.…”

Rehydration strategies in infants and children with acute gastroenteritis refusing or not tolerating an oral fluid challenge

“…In support of this, 34 out of 56 (61%) nurses also felt that NG tube insertion was more distressing for a child than IV cannulation 12. It is unclear if proven adjuncts for patient comfort such as topical local anaesthetic preparations13 and cold sprays14 were employed to facilitate the comfortable insertion of IV cannulae in this study.…”

Lidocaine spray vs mepivacaine local infiltration for suturing 1st/2nd grade perineal lacerations: a randomised controlled non-inferiority trial

“…Furthermore, compared to the infiltration of local anesthetic, there is a lower risk of bleeding [8,9]. The efficacy of non-injective local anesthetics for minor surgical procedures has already been demonstrated in various fields, both in the obstetric-gynecological and other disciplines [8,[23][24][25][26][27][28]. In particular, as regards the gynecological procedures, the studies have focused on the effects of various topical anesthetics in the puerperium, of EMLA during suturing of perineal lacerations, of lidocaine spray as anesthetic therapy in the second stage of labor or other gynecological procedures, such as colposcopy, outpatient hysteroscopy, and endometrial biopsies.…”