Emerging potential of immunopeptidomics by mass spectrometry in cancer immunotherapy
Yuriko Minegishi,
Yoshimi Haga,
Koji Ueda
Abstract:With significant advances in analytical technologies, research in the field of cancer immunotherapy, such as adoptive T cell therapy, cancer vaccine, and immune checkpoint blockade (ICB), is currently gaining tremendous momentum. Since the efficacy of cancer immunotherapy is recognized only by a minority of patients, more potent tumor‐specific antigens (TSAs, also known as neoantigens) and predictive markers for treatment response are of great interest. In cancer immunity, immunopeptides, presented by human le… Show more
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