Emerging perspectives of plant-derived nanoparticles as effective antimicrobial agents

Tabasum, Humairah; Bhat, Basharat Ahmad; Sheikh, Bashir Ahmad; Mehta, Vaibhavkumar N.; Rohit, Jigneshkumar V.

doi:10.1016/j.inoche.2022.110015

Cited by 4 publications

(3 citation statements)

References 126 publications

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“…While antibiotic resistance results from both judicious and injudicious antibiotic use, the quest for new antimicrobial sources has become imperative (8,9). The resurgence in the valorization of medicinal plants for their therapeutic potential has shed light on their capacity to yield novel antibacterial compounds (2,15,18,(43)(44)(45). Pongamia pinnata, commonly referred to as Karanja, has a storied history of medicinal use and has recently been subjected to scientific scrutiny for its antibacterial efficacy (6,43,(46)(47)(48).…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Analysis and Antimicrobial Activity of Pongamia Pinnata: A Comprehensive Study

Sattar,

Raza,

Sarfraz

et al. 2024

JHRR

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Background: Antimicrobial resistance (AMR) poses a significant global health challenge, exacerbated by the misuse of antimicrobial agents. With the rising prevalence of AMR in various plant and animal pathogens, there is an urgent need to explore alternative therapeutic options. Plant extracts, historically utilized for disease treatment, offer a promising avenue. Pongamia pinnata, also known as Indian Karanja, is notable for its rich phytochemical content and has been the subject of recent scientific interest. Objective: The primary aim of this study is to investigate the antimicrobial efficacy of P. pinnata extracts, prepared using the Ultrasonic Assisted Extraction (UAE) method, against a range of bacterial and fungal species known to exhibit AMR. Methods: In this study, an experimental laboratory design was utilized to evaluate the antimicrobial properties of Pongamia pinnata. Aqueous and alcoholic extracts of P. pinnata were prepared and subjected to biochemical analysis to identify the spectrum of phytochemicals present. The antimicrobial activity of these extracts was then assessed using the well-diffusion method against selected bacterial and fungal pathogens. Results: Both aqueous and alcoholic extracts of P. pinnata demonstrated significant antimicrobial effects against the tested microbial species. The study highlights the potent antimicrobial properties of P. pinnata, attributed to its diverse phytochemical composition. Conclusion: The findings of this study underscore P. pinnata as a valuable source of natural antimicrobial agents. Its efficacy against AMR pathogens suggests its potential application in the development of new treatments for infectious diseases. P. pinnata holds promise for medicinal use, particularly in contexts where conventional antibiotics are ineffective.

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Section: Discussionmentioning

confidence: 99%

Phytochemical Analysis and Antimicrobial Activity of Pongamia Pinnata: A Comprehensive Study

Sattar,

Raza,

Sarfraz

et al. 2024

JHRR

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“…Food safety issues caused by foodborne pathogens have been a continuous concern, highlighting the need for the development of antimicrobial agents [4]. Such agents are vital in preventing foodborne diseases by inactivating or inhibiting pathogenic microorganisms [5]. Antibacterial agents can be divided into three categories: inorganic, organic, and natural [6].…”

Section: Introductionmentioning

confidence: 99%

Utilizing Imine Bonds to Create a Self-Gated Mesoporous Silica Material with Controlled Release and Antimicrobial Properties

et al. 2023

Nanomaterials

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In recent years, silica nanomaterials have been widely studied as carriers in the field of antibacterial activity in food. Therefore, it is a promising but challenging proposition to construct responsive antibacterial materials with food safety and controllable release capabilities using silica nanomaterials. In this paper, a pH-responsive self-gated antibacterial material is reported, which uses mesoporous silica nanomaterials as a carrier and achieves self-gating of the antibacterial agent through pH-sensitive imine bonds. This is the first study in the field of food antibacterial materials to achieve self-gating through the chemical bond of the antibacterial material itself. The prepared antibacterial material can effectively sense changes in pH values caused by the growth of foodborne pathogens and choose whether to release antibacterial substances and at what rate. The development of this antibacterial material does not introduce other components, ensuring food safety. In addition, carrying mesoporous silica nanomaterials can also effectively enhance the inhibitory ability of the active substance.

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“…In present study, the Nyctanthes arbor-tristis flower extracts were used for the synthesis of ZnO NPs, which is further used as nanoadsorbent for removing metal contaminants from the water sample. Although the flower extract of Nyctanthes arbortristis was used for preparing gold nanoparticles [32], however, no studies has been reported on the preparation of ZnO NPs from this plant. Several characterization techniques viz.…”

Section: Introductionmentioning

confidence: 99%

Effective removal of selective heavy metal ions from aqueous solution through green synthesized zinc oxide nanoparticles

Kashyap,

Moharana,

Agrawal

et al. 2023

ajc

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The presence of pollutants such as harmful heavy metals in aqueous system is currently one of the largest environmental problems. Due to unmanaged discharge from numerous industries, this system is a serious problem in the major cities of developing nations. Due to the adverse effects on the environment and potential to cause cancer in humans, these contaminants are anticipated to require special consideration. Pollution clearance is a difficult problem that needs to be tackled if adverse effects on people and the environment are to be avoided or minimized. The main objective of this present research is to synthesize zinc oxide nanoiparticles (ZnO-NPs) from Nyctanthus arbor-tristis flower in a safe, non-toxic, and ecologically friendly manner. The adsorption of U(VI), Pb(II), Cr(VI) and Cd(II) ions from aqueous solutions by Nyctanthus arbor-tristis flower extract was investigated under laboratory conditions to assess its potential in removing these metal ions. The impacts of the experimental factors, such as ZnO-NPs dosage, solution pH, and contact time, were investigated. The study shows that the majority of the toxic metal ions can be adsorbed from the solution in a relatively short duration of time under ambient conditions. The adsorption behavior of toxic metal ions onto the ZnO-NPs was analyzed with Freundlich as well as Langmuir rate equations and the results were supported by the pseudo-second-order kinetic models. The study provides a safe, non-toxic, and eco-friendly green synthesis method and also demonstrated excellent performance of the synthesized ZnO-NPs.

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Emerging perspectives of plant-derived nanoparticles as effective antimicrobial agents

Cited by 4 publications

References 126 publications

Phytochemical Analysis and Antimicrobial Activity of Pongamia Pinnata: A Comprehensive Study

Phytochemical Analysis and Antimicrobial Activity of Pongamia Pinnata: A Comprehensive Study

Utilizing Imine Bonds to Create a Self-Gated Mesoporous Silica Material with Controlled Release and Antimicrobial Properties

Effective removal of selective heavy metal ions from aqueous solution through green synthesized zinc oxide nanoparticles

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