Elimination of a Community-Acquired Methicillin-Resistant Staphylococcus aureus Infection in a Nurse With Atopic Dermatitis

Colonization with community‐acquired methicillin‐resistantStaphylococcus aureusin children with atopic dermatitis: a cross‐sectional study

“…Atopic dermatitis patients are rarely admitted to hospital and are therefore more likely to become colonized or infected with CA‐MRSA. Community‐acquired MRSA can carry a gene encoding Panton–Valentine leukotoxin (PVL), which has been associated with severe or fatal infections in otherwise healthy children and adults 28–33 . In addition, more than 50% of PVL‐positive MRSAs are resistant to mupirocin, 34 which has changed the way MRSA‐colonized patients are managed.…”

“…Community-acquired MRSA can carry a gene encoding Panton-Valentine leukotoxin (PVL), which has been associated with severe or fatal infections in otherwise healthy children and adults. [28][29][30][31][32][33] In addition, more than 50% of PVL-positive MRSAs are resistant to mupirocin, 34 which has changed the way MRSA-colonized patients are managed. Knowing the genotypic traits of the MRSA isolates has direct implications for clinical management.…”

Panton–Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus outbreak among healthcare workers in a long-term care facility

“…1 The sustained elimination of MRSA carriage within a healthcare facility may prove difficult and take several courses. 28 A recent meta-analysis concluded that there is insufficient evidence to support topical or systemic therapy for eradicating MRSA carriage. 29 In the current outbreak, our decision for blanket decolonization of all residents and staff with mupirocin could be regarded as excessive, especially given the paucity of evidence of transmission other than between practice nurses, the absence of severe disease, and no evidence of onward transmission to residents.…”

Sensitizing potential of triclosan and triclosan-based skin care products in patients with chronic eczema

“…Triclosan is increasingly used in preventing infections in intensive care units as different studies have documented the elimination of methicillin‐resistant Staphylococcus aureus form by using hand detergents based on triclosan (12–14). Moreover, controlled studies have shown the efficacy of triclosan in the treatment of moderate to severe atopic dermatitis and contact dermatitis (12,15,16), with reduced skin colonization by different bacteria and Candida spp., and also with substantial improvement of pruritus and skin signs (15,16). Besides, it has been demonstrated that triclosan can decrease the wheal induced by intradermal injection of histamine.…”