Elicitor-Induced Cellular and Molecular Events Are Responsible for Productivity Enhancement in Hairy Root Cultures: An Insight Study

Abstract

A wide range of external stress stimuli triggers a plant cell to undergo a complex network of reactions that ultimately lead to the synthesis and accumulation of secondary metabolites. These secondary metabolites help the plant to survive under stress challenge. The potential of biotic and abiotic elicitors for the induction and enhancement of secondary metabolite production in various culture systems including hairy root (HR) cultures is well-known. The elicitor-induced defense responses involves signal perception of elicitor by a cell surface receptor followed by its transduction involving some major cellular and molecular events including activation of major secondary message signaling pathways. This result in induction of gene expressions escorting to the synthesis of various proteins mainly associated with plant defense responses and secondary metabolite synthesis and accumulation. The review discusses the elicitor-induced various cellular and molecular events and correlates them with enhanced secondary metabolite synthesis in HR systems. Further, this review also concludes that combining elicitation with in-silico approaches enhances the usefulness of this practice in better understanding and identifying the rate-limiting steps of biosynthetic pathways existing in HRs which in turn can contribute towards better productivity by utilizing metabolic engineering aspects.

Purification and Characterization of Alkaline Pectin Lyase from a Newly Isolated Bacillus clausii and Its Application in Elicitation of Plant Disease Resistance

“…), microorganisms (chitin, glucans, etc. ), and G proteins which are bound to the receptors and act by activating or inactivating ion channels or enzymes [35]. A number of chemical compounds, microorganisms, and acidic pectinases have been reported to induce resistance against plant diseases [11].…”

Establishment of suspension cultures of Salvadora persica L. for benzyl isothiocyanate production

“…In each column, mean followed by the same subscripted letter was not significantly different (p < 0.05) according to the Duncan's multiple range test It is observed that BITC production is highly affected by the addition of biotic elicitors. Therefore, elicitation offers an attractive strategy for increasing the secondary metabolite in vitro production [31] . This study showed that both chitosan and salicylic acid increased accumulation of BITC in callus culture of S. persicaover the control.…”

Contribution of Biotechnological Tools in the Enhancement of Secondary Metabolites in Selected Medicinal Climbers

“…Elicitors are mainly of three types; biotic, abiotic and physical. Elicitors can enhance or even induce the biosynthesis of certain metabolites (Goel et al 2011 ) .…”