volume 28, issue 3, P503-514 2012
DOI: 10.3233/jad-2011-111352
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Martha Dlugaj, Marcus Gerwig, Natalia Wege, Johannes Siegrist, Klaus Mann, Martina Bröcker-Preuß, Nico Dragano, Susanne Moebus, Karl-Heinz Jöckel, Beate Bokhof, Stefan Möhlenkamp, Raimund Erbel, Christian Weimar

Abstract: As high-sensitivity C-reactive protein (hsCRP) seems to be associated with an increased risk of cognitive decline, this nested case-control study examined the relation of hsCRP and mild cognitive impairment (MCI) at different time points. 148 MCI cases (106 amnestic, 42 non-amnestic (aMCI/naMCI)) and 148 matched controls were identified from a prospective population based cohort study of 4,359 participants (aged 50-80). HsCRP levels were measured 5 years before (baseline) and at the time of neuropsychological …

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