Electrospinning of Scaffolds from the Polycaprolactone/Polyurethane Composite with Graphene Oxide for Skin Tissue Engineering

Sadeghianmaryan, Ali; Karimi, Yaghoub; Naghieh, Saman; Sardroud, Hamed Alizadeh; Gorji, Mohsen; Chen, Daniel

doi:10.1007/s12010-019-03192-x

Cited by 52 publications

(33 citation statements)

References 21 publications

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“…Combining PU with PCL and graphene oxide (GO), the resulting nanofiber mats showed an increasing fiber diameter with increasing GO concentration [120]. Seeding human skin fibroblast cells on them, Sadeghianmaryan et al found good biocompatibility and showed that GO could significantly increase the hydrophilicity and biocompatibility, as compared to pure PU/PCL nanofiber mats, in this way leading to stretched cell growth on the more "cell-friendly" surface.…”

Section: Polyurethanementioning

confidence: 99%

Electrospun Nanofibrous Membranes for Tissue Engineering and Cell Growth

Tanzli

Ehrmann

2021

Applied Sciences

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In biotechnology, the field of cell cultivation is highly relevant. Cultivated cells can be used, for example, for the development of biopharmaceuticals and in tissue engineering. Commonly, mammalian cells are grown in bioreactors, T-flasks, well plates, etc., without a specific substrate. Nanofibrous mats, however, have been reported to promote cell growth, adhesion, and proliferation. Here, we give an overview of the different attempts at cultivating mammalian cells on electrospun nanofiber mats for biotechnological and biomedical purposes. Starting with a brief overview of the different electrospinning methods, resulting in random or defined fiber orientations in the nanofiber mats, we describe the typical materials used in cell growth applications in biotechnology and tissue engineering. The influence of using different surface morphologies and polymers or polymer blends on the possible application of such nanofiber mats for tissue engineering and other biotechnological applications is discussed. Polymer blends, in particular, can often be used to reach the required combination of mechanical and biological properties, making such nanofiber mats highly suitable for tissue engineering and other biotechnological or biomedical cell growth applications.

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Section: Polyurethanementioning

confidence: 99%

Electrospun Nanofibrous Membranes for Tissue Engineering and Cell Growth

Tanzli

Ehrmann

2021

Applied Sciences

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“…Although there are a limited number of studies on FTIR analysis of decellularized native tissues, it basically gives some clear clues regarding the basic composition of ECM. PCL basically has characteristic peaks in wavelength ranges of 1150-1250 cm -1 (COC, -COC-), 1250-1300 cm -1 (CC) 1700-1750 cm -1 (CH 2 ) and 2800-3000 cm -1 (CH 2 ) [22,23].…”

Section: Resultsmentioning

confidence: 99%

Development of a nanofibrous scaffold based on bovine tissue-derived ECM and Poly(ε-caprolactone) for tissue engineering applications

Parmaksız¹

2021

Hittite J. Sci. Eng.

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T he main focus of tissue engineering approach is the development of biomaterial scaffolds exhibiting similarity to the three-dimensional (3D) architecture, and its natural bioactive microenvironment of the target tissue or organ. Up till now, this goal has not been fully achieved, owing to the difficulty in completely mimicking the versatile bio-functional composition and structure of the natural extracellular matrix (ECM) [1]. A number of scaffold manufacturing techniques such as, solvent casting and electrospinning have been utilized in order to obtain 3D porous or nanofibrous scaffolds somewhat architecturally resembling the natural ECM by using natural or synthetic biocompatible polymers [2]. In particular, FDA-approved synthetic resorbable polymers such as poly(ε-caprolactone) (PCL), poly(lactic-co-glycolic acid) (PLGA), and other α-hydroxy acid polymers etc. in such forms have been widely utilized in a variety of tissue engineering applications, some of which have reached clinical applications [3]. However, in addition to being biocompatible and structurally-resembling the tissue, tissue engineering scaffolds are expected to support cell attachment and proliferation, as well as promote angiogenesis, and regeneration when Article History:

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“…49 So it is often blended with other polymers in electrospinning to expedite overall polymer erosion 45 and improve the wettability and biocompatibility. 50 PLA. Polylactic acid (PLA) is another biocompatible material with good mechanical strength that has been extensively utilized by electrospinning in the treatment of periodontitis.…”

Section: Pclmentioning

confidence: 99%

Biodegradable engineered fiber scaffolds fabricated by electrospinning for periodontal tissue regeneration

Ren

et al. 2020

J Biomater Appl

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Considering the specificity of periodontium and the unique advantages of electrospinning, this technology has been used to fabricate biodegradable tissue engineering materials for functional periodontal regeneration. For better biomedical quality, a continuous technological progress of electrospinning has been performed. Based on property of materials (natural, synthetic or composites) and additive novel methods (drug loading, surface modification, structure adjustment or 3 D technique), various novel membranes and scaffolds that could not only relief inflammation but also influence the biological behaviors of cells have been fabricated to achieve more effective periodontal regeneration. This review provides an overview of the usage of electrospinning materials in treatments of periodontitis, in order to get to know the existing research situation and find treatment breakthroughs of the periodontal diseases.

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Electrospinning of Scaffolds from the Polycaprolactone/Polyurethane Composite with Graphene Oxide for Skin Tissue Engineering

Cited by 52 publications

References 21 publications

Electrospun Nanofibrous Membranes for Tissue Engineering and Cell Growth

Electrospun Nanofibrous Membranes for Tissue Engineering and Cell Growth

Development of a nanofibrous scaffold based on bovine tissue-derived ECM and Poly(ε-caprolactone) for tissue engineering applications

Biodegradable engineered fiber scaffolds fabricated by electrospinning for periodontal tissue regeneration

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