Electrooxidation of 5-substituted indoles

Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization

“…In this study electrochemical behavior of selective MLT analogues through mechanistic studies was investigated. It was observed that oxidation occurred firstly on the nitrogen atom of indole ring leading finally to hydroxylation of the benzene ring [36][37][38][39]42 . This investigation gives some suggestions about the possible in vivo metabolism of newly synthesized compounds.…”

“…Comparative study on indole, synthesized indole compounds, indole-3-acetic acid, etodolac, fluvastatine, and ziprasidon were realized by CV at a function of pH in order to identify the oxidation process of the synthesized compounds. It was assumed that oxidation occurred firstly on the nitrogen atom of indole ring, which is electroactive in both acidic and basic media, leading finally to hydroxylation of the benzene ring [36][37][38][39]42 . The electrochemical oxidation of indole derivatives with a substituent presented similar features to the indole electroactive centre.…”

Experimental thermochemical study of 5-bromoindole and 5-bromoindoline

“…These compounds have also attracted great attention in pharmacology, mainly because of their ability to develop antifungal and antibacterial agents, but also as candidates for anti-oxidant, direct oxidation/reduction of biomolecules, and other biological activities [1][2][3][4]. Due to their presence in water and soil as persistent organic pollutants, these organobromine compounds have also been the focus of considerable research work to determine their toxicity effects on the environment [4].…”

“…Bromoindoles are compounds with high potential for applications in various domains, especially in the electrochemical industry as electrocatalysts, anode materials in batteries, anticorrosion coating, and fast response potentiometric sensors [1,2]. These compounds have also attracted great attention in pharmacology, mainly because of their ability to develop antifungal and antibacterial agents, but also as candidates for anti-oxidant, direct oxidation/reduction of biomolecules, and other biological activities [1][2][3][4].…”

Electrochemical Behavior of Indoles with Methyl, Benzyl, and Dibenzyl-4-yl Groups

“…The structure and polymerization mechanism of polyindole (PI) and of its derivatives is controversial [3][4][5][6][7], and even some experimental results seem to be contradictory. It is generally accepted that oxidation generates the indolyl radical cation, which can be deprotonated.…”