Electromagnetic fields induce neural differentiation of human bone marrow derived mesenchymal stem cells via ROS mediated EGFR activation

Effects of extremely low frequency electromagnetic field (ELF-EMF) on catalase, cytochrome P450 and nitric oxide synthase in erythro-leukemic cells

“…It can initiate a number of biochemical and physiological alterations in biological systems of different species [18,21,40]. The biological effects in cell lines exposed to ELF-EMFs have been frequently noted [19,24,35,33,42]. However, despite the large number of studies, an understanding is still lacking [12,25,46].…”

Expression levels of PDYN and OPRM1 genes in SH-SY5Y cells exposed to 50 Hz electromagnetic field

“…Previous studies have demonstrated that ELF-EMF is associated with production of ROS. [16][17][18] Moreover, reduced PDYN expression in the human brain is associated with opiate dependency. 35,36 Interestingly, in the present study the continuous exposure condition of ELF-EMF was associated with the lower expression levels of the PDYN.…”

“…15 It has been reported that ELF-EMF enhanced production of reactive oxygen species (ROS). [16][17][18] Cells maintain redox balance through production of ROS and cellular antioxidant capacity. The altered balance between generation and elimination of ROS plays a critical role in a variety of multifactorial complex traits including neurodegenerative diseases.…”

Effects of 915 MHz Radiofrequency Identification Electromagnetic Field Exposure on Neuronal Precursor Cells in the Dentate Gyrus of Adult Rat Brains

“…Recent in vitro studies have suggested that exposure of human bone marrow-derived mesenchymal stem cells to ELF-EMF decreases their proliferation rate instead of causing an increase in both osteogenic and neuronal differentiation [12][13][14][15]. To explore the effects of RF-EMFs on cultured neuronal cells, the growth and differentiation of a standard neuronal-like cell line was studied.…”