Electrodeposited copper nanocubes on multi-layer graphene: A novel nanozyme for ultrasensitive dopamine detection from biological samples

Highly sensitive amperometric sensors based on laccase-mimetic nanozymes for the detection of dopamine

“…The prepared sensors exhibit a wide linear operating ranges as well as a low detection limit in comparison with the described nanozyme-based sensors (CuNCs–Gr/SPCE, MnO 2 /GQD, hemin-doped HKUST-1/rGO) and laccase-based bionanosensors (Lac–GA–NH 2 C 2 H 4 S, Lac–HNT–ImS 3 –14/CPE, Lac–Glu–AuNPs/CPE). 34–40 The sensor described here, nAuCu/nAuPt/GCE has a 60-fold higher sensitivity compared to Hemin-doped HKUST-1/rGO and Lac–GA–NH 2 C 2 H 4 S–AuNS/GC sensors. 34,36…”

“…10 However, due to the high cost of laccase and its nonsufficient stability (susceptibility to changes of pH and temperature during the storage) it is advantageous to substitute laccase by nanoparticles (NPs) possessing laccase-like activity. [11][12][13][14][15] A number of low-cost laccase-like nanozymes NZs possessing high catalytic activity have been described and used for the development of DA-sensitive sensors, in particular, nanoparticles of Ni, 16 Pd, 17 Co, 18 Au, 19 Cu, 20 different nanooxides and suldes (FePt-Fe 3 O 4 , Fe 3 O 4 , Au@Fe 3 O 4 , ZnFe 2 O 4 , MoS 2 ), some polymers, carbon nanomaterials (single-walled nanotubes, multi-walled nanotubes) and carbon-based materials functionalized with metal NPs. [21][22][23][24][25][26] Detection of DA by electrochemical methods is not an easy task and is complicated by other redox biomolecules that can be oxidized at similar potentials, such as ascorbic acid or uric acid.…”

Hybrid nanomaterial-based indirect electrochemical sensing of glyphosate in surface water: a promising approach for environmental monitoring

“…For comparison, a few and multi-layer graphene nanomaterial (GR) was also synthesized using the electrochemical exfoliation method reported in a previous study. 33…”

“…The selected volume and concentration of the dispersed graphene based nanomaterial were optimized in previous studies. 32,33 All the prepared sensors were stored at room temperature, in a dry place. The screenprinted carbon electrode (SPCE) functionalized with GR and Au-GR was further denoted as GR/SPCE and Au-GR/SPCE, respectively.…”

The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications

“…In the existence of other neurotransmitters, the developed sensor showed remarkable selectivity for DA. The reliability of the approach was demonstrated by the 95–100% recovery for the exposure of DA in human blood plasma samples [ 107 ]. Real-time monitoring of DA in living cells is essential for research and biological diagnosis of numerous central nervous system illnesses.…”