Effiziente Synthese von 5-Methoxy-2-nitrophenol

Benzoxazinoids: Reactivity and Modes of Action of a Versatile Class of Plant Chemical Defenses

“…30 On the other hand, racemic mixtures of synthetic BXD methyl acetals have been successfully resolved by all three methods, confirming their stability towards hydrolysis and racemization by ring opening. It is interesting to note that all known benzoxazinone glucosides produced by plants are (2R)-2-β-D-glucosides [31][32][33][34] that upon glucosidase activity yield racemic mixtures of (2R) and (2S) aglucones.…”

First discrimination of enantiomeric cyclic hemiacetals and methyl acetals derived from hydroxamic acids and lactams of Gramineae by means of 1H NMR using various chiral solvating agents

“…The first discrimination of enantiomeric cvclic methvl acetals M , 9 and 10, derived from hydro-xamic acids and lactams with the 2H-1,4,-benzoxazin-3(4H)-one and…”

Novel 3‐(2‐Oxo‐2H‐benzo[b][1,4]oxazin‐3‐yl)propanoates from Dimethyl‐2‐oxoglutarate and Test of Their Biological Activity

“…Here, we report a facile synthesis of novel 3-(2-oxo-2Hbenzo[b] [1,4]oxazin-3-yl)propanoates from 2-aminophenols and dimethyl-2-oxoglutarate and results of their antimicrobial and antifungal testing. [1,4]oxazin-3-yl)propanoates 3a-e. Dimethyl-2-oxoglutarate 2 (Scheme 1) was prepared in a high yield (85%) by esterification of 2-oxoglutaric acid with methanol according to the procedure formerly reported [20]. As shown in Scheme 1, the reaction of dimethyl-2-oxoglutarate with an equimolar amount of 2-aminophenol 1a, 2-amino-5-methylphenol 1b, 2-amino-4methylphenol 1c, 2-amino-3-methylphenol 1d, and 2-amino-4-chlorophenol 1e afforded the corresponding 3-(2-oxo-2H-benzo[b] [1,4]oxazin-3-yl)propanoates 3a-e in good yields under very mild conditions.…”