Efficient Synthesis of 5-(4-(Substituted [1,1′-Biphenyl]-4-yl-methoxy)benzyl)thiazolidine-
2,4-diones under Microwave Irradiation using Suzuki Coupling Reaction
and their Biological Screening
Abstract:In present study, an efficient and greener protocol is developed for the synthesis of 5-(4-(substituted
[1,1′-biphenyl]-4-yl-methoxy)benzyl)-thiazolidine-2,4-diones by using microwave irradiations. Here,
a one-pot reaction between 5-(4-((4-bromobenzyl)oxy)benzyl)thiazolidine-2,4-dione, substituted aryl
boronic acid and K2CO3 in the presence of toluene:water:ethanol solvents under conventional heating
methods and microwave irradiation methods is reported. All the final compounds were characterized by
FT-IR, 1H … Show more
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