“…The most frequently used irrigants with organolithic effects are sodium hypochlorite, hydrogen peroxide, chloramines, chlorhexidine. The final irrigants with mineralolithic effect are 17% NaEDTA, 10% citric acid, and the solution of recent date -MTAD (Biopure, Tulsa Dentsply, Tulsa OK, USA) -a combination of tetracyclines containing weak organic acids and anion-active substances (Torabinejad et al, 2002Kando et al, 1991;Di Lenardda, 2000;Mitić et al, 2009;Yamaguchi et al, 1996;Haapasalo et al, 2005;Mitić, 2010). The purpose of the present research was to analyze the surface of intracanal dentin after instrumentation and irrigation by organolithic agents (2.5% sodium hypochlorite, 3% hydrogen peroxide, 2% chlorhexidine) and final irrigation by mineralolithic effect solutions (17% NaEDTA, 10% citric acid and MTAD solution).…”