volume 5, issue 10, Pe13438 2010
DOI: 10.1371/journal.pone.0013438
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Abstract: BackgroundIntermittent preventive treatment (IPT) is a promising malaria control strategy; however, the optimal regimen remains unclear. We conducted a randomized, single-blinded, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of a single course of sulfadoxine-pyrimethamine (SP), amodiaquine + SP (AQ+SP) or dihydroartemisinin-piperaquine (DP) among schoolchildren to inform IPT.MethodsAsymptomatic girls aged 8 to 12 years and boys aged 8 to 14 years enrolled in two primary schools i…

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