Efficacy of turmeric (Curcuma longa) and garlic (Allium sativum) on Eimeria species in broilers

Abstract

In this study, powders were evaluated for their anticoccidial effects. In in vitro, sporulated oocysts of mixed Eimeria species isolated from naturally infected chickens were randomly assigned to 10, 5, 2.5, 1.25, 0.6, 0.3, 0.2 and 0.08 g turmeric and garlic powders /liter distilled water (g/L). The efficacy of garlic was higher (up to 80%) than turmeric (up to 66.6%) at different concentrations. In the in vivo study, one-day old chicks were divided into 7 equal groups. All groups were infected with 10.000 viable sporulated oocysts of mixed Eimeria spp. orally except G7 (-ve control). G1 and G2 were infected and supplemented with turmeric powder at 10 and 5 g/L, respectively, G3 and G4 were infected and supplemented with garlic powder at 10 and 5 g/L, respectively. G5 was infected and treated with Amprolium at 1.25 g/L, G6 (+ve control) infected, non-treated and G7 was non-infected & non-treated. Clinical signs and lesion score were less sever in garlic supplemented groups compared with turmeric supplemented groups. Reduction of total oocyst count in garlic supplemented group more than turmeric supplemented group. It is concluded that Garlic powder was more effective than turmeric powder in treatment and control of coccidiosis.

Anticoccidial Activity of Aloe debrana and Aloe pulcherrima Leaf Gel against Eimeria Oocysts

“…In agreement with the current findings, similar in vitro effects of Aloe vera and Aloe spicata on the inhibition of the sporulation of avian coccidian oocysts were reported by Mwale et al [53] and they found that Aloe spicata had higher sporulation inhibition efficacy at 30% concentration (65.42%) while A. vera had the least number of sporulated oocyst at 45% concentration with an inhibition percentage of 62.5%. The 79.35% inhibition efficacy of A. debrana at 30% (w/v) concentration found in this study is consistent with the findings by El-Khtam et al [54] who reported 80% sporulation inhibition effects of garlic powder. Furthermore, El-Khtam et al [54] reported 66% inhibition efficacy of Values in a column followed by the same superscripts are not significantly different (P > 0:05) while different superscripts indicate statistical difference (P < 0:05); AD: Aloe debrana.…”

“…The 79.35% inhibition efficacy of A. debrana at 30% (w/v) concentration found in this study is consistent with the findings by El-Khtam et al [54] who reported 80% sporulation inhibition effects of garlic powder. Furthermore, El-Khtam et al [54] reported 66% inhibition efficacy of Values in a column followed by the same superscripts are not significantly different (P > 0:05) while different superscripts indicate statistical difference (P < 0:05); AD: Aloe debrana. Values in a column followed by the same superscripts are not significantly different (P > 0:05) while different superscripts indicate statistical difference (P < 0:05); AP: Aloe pulcherrima.…”

“…Sacan et al [70] conclude that A. vera leaf gel extract could be used as a source of natural enzyme inhibitor and antioxidant activity in pharmaceutical, cosmetic, and food industries. According to El-Khtam et al [54], antioxidantrich plants may be lethal to the parasites by inducing oxidative stress and neutralize reactive oxygen species and have potential benefits in treating coccidial infections.…”

The Administration of Garlic Extract on Eimeria stiedai Oocysts and the Hematological Profile of the Coccidia Infected Rabbits

“…This in vitro study conducted on garlic supported the previous research that garlic might be used as antcoccidiosis. Garlic has several active compounds including allicin, alliin, ajoene, diallyl sulfide, dithiin, and allylcystein, in which allicin may inhibit E. tenella sporulation in chickens (El-Khtam et al, 2014;Pourali et al, 2014). The other natural plant functioning as an anticoccidiosis is banana stem.…”

“…Garlic can be used as antibacterial (Tipu et al, 2002;Safithri et al, 2011), antiparasitic, and anticoccidial agents in sheep (Worku, 2009) and chickens (Pourali et al, 2014;El-Khtam et al, 2014). Garlic and its sulfur compounds, allicin, aliin, ajoene, diallyl sulfide, dithiin, and allylcysteine are reported to have broad antimicrobial activities which can eliminate the negative factor of microbial infections.…”