Aims
Internal and external triggers affect seasonal and circadian variations of myocardial infarction (MI). We aimed to assess sex differences in common triggers of MI.
Methods
A nationwide, retrospective cross-sectional postal survey study was conducted. Individuals who experienced a MI during holidays and weekdays were identified through the SWEDEHEART registry. 27 potential MI-triggers were rated in regards of occurring more or less than usual during the last 24 hours before the MI. Three areas were covered: activities, emotions and food- or alcohol consumption. A logistic regression model was used to identify sex differences for each trigger and odds ratios (OR) were reported.
Results
451 patients, of whom 317 were men responded. The most common reported triggers were stress (35.3%), worry (26.2 %), depression (21.1%) and insomnia (20.0%). Women reported emotional triggers including sadness (OR 3.52, 95% CI 1,92-6,45), stress (OR 2.38, 95% CI 1.52-3.71), insomnia (OR 2.31, 95% CI 1,39-3,81) and upset (OR 2.69, 95% CI 1.47-4.95) to a greater extent than men. Outdoor activity was less reported by women, OR 0.35, 95% CI 0.14-0.87. No significant sex differences were found in other activities or food and alcohol consumption.
Conclusion
Self-experienced stress and distress were higher among women prior to myocardial infarction compared to men. Understanding sex perspectives in acute triggers may help us find preventive strategies and to reduce the excess numbers of MI.