Efficacy of Polidocanol Foam versus Liquid in Sclerotherapy of the Great Saphenous Vein: A Multicentre Randomised Controlled Trial with a 2-year Follow-up

Abstract

The sclerosant foam used in this study was more than twice as effective as the liquid from which the foam was prepared.

Comparing ultrasound guided foam sclerotherapy with surgical treatment in patients of varicose veins

“…and did not require any active intervention, which are again comparable to the published studies. [23][24][25] Pain and pigmentations were the two most important complication in foam group in our study which is in accordance with the literature. Pain in 4 (16%) patients and pigmentation 5 (20%) patients.…”

“…Pain in 4 (16%) patients and pigmentation 5 (20%) patients. [23][24][25] No major complication was found in UGFS group which is also established in literature. [23][24][25] So foam sclerotherapy is quite a safe procedure if done with proper USG guidance and care.…”

Applications of Polidocanol in Varicose Vein Treatment Assisted by Exposure to Nd:YAG Laser Radiation

“…Medical observations prove that foam sclerotherapy is preferable instead of the use of liquid sclerosing substances (Ouvry et al, 2008). Detergent-like sclerosing agents can be transformed into fine-bubbled foam by special techniques.…”

“…There are many works providing good results about the use of POL foam sclerotherapy (Alos et al, 2006;Cabrera et al, 2000;Cavezzi and Frullini, 1999;Frullini, 2000;Gachet, 2001;Garcia-Mingo, 1999;Hsu and Weiss, 2003;Ouvry et al, 2008;Rabe et al, 2008;Redondo and Cabrera, 2005;Santos, 2008;Tessari, 2000). The ability to be agitated and foamed increases the potency of detergents from 2 to 4 times by mechanically displacing blood and thus maximizing surface area and time in contact with endothelium.…”

Efficacy and safety of ultrasound guided foam sclerotherapy with sodium tetradecyl sulphate for residual and minor varicosities

“…Similar follow-up has also been suggested by several other authors. [12][13][14][15] An ultrasound examination was done a week after therapy showed optimum obliteration of the treated vein in all the cases and also showed no signs of DVT. Thus re-sclerotherapy was not required.…”