Efficacy of mesenchymal stem cells in healing of meniscus tear

Abstract

The aesthetic appearance of the thumb hasn't been analysed to a similar extent as thumb function which would aid during reconstructive surgeries of the thumb and first web space and analyse its outcome. The purpose of this study is to determine the relative length, girth, nail width of thumb with respect to the index finger and intermetacarpal distance. Measurement of the 1 st web space arc radius has been done to tackle the problem of webbing which is not addressed by IMD and palmar abduction angles. A total of 482 hands in 241 subjects were studied to measure the relative length of the thumb with respect to the index finger, the relative nail width of thumb with respect to index finger, the relative girth of IP joint of thumb with respect to PIP joint of index finger and Intermetacarpal distance was calculated. The 1 st web space arc radius was calculated by the "best arc fit" with the thumb in maximum radial abduction using a radius gauge. The data collected was analysed by age, gender, laterality of the hand and the height and weight of the child. Hands of subjects of which with a mean age of years were analysed. The relative Thumb length, girth and nail width remained independent of age. It has been observed that the reliability of the measurements between the right and left web space arc radius measurement is significant . The provided would help reconstructive surgeons analyse aesthetic outcomes of reconstructive surgeries intraoperatively and post operatively. A correlation between the 1 st web space arc radius of right and left hands would help predict the expected post-operative outcome.

Meniscus Repair Techniques

“…90 Another recent randomized, double-blinded trial performed intra-articular injection of mesenchymal stem cells in 2 groups of 15 patients with clinical and imaging diagnosed meniscus tears. 91 Significant clinical improvement in pain and resolution of MRI signal change was noted in the group that received the stemcell injection in comparison to the placebo control group.…”

“…A randomized, double-blinded trial demonstrated meniscus regeneration on the basis of increased size (24%) on MRI and significant reductions in pain in patients treated with mesenchymal stem cell injections that had a prior medial meniscectomy 90. Another recent randomized, double-blinded trial performed intra-articular injection of mesenchymal stem cells in 2 groups of 15 patients with clinical and imaging diagnosed meniscus tears 91. Significant clinical improvement in pain and resolution of MRI signal change was noted in the group that received the stem-cell injection in comparison to the placebo control group.…”