Efficacy of low‐level laser therapy associated with fluoride therapy for the desensitisation of molar‐incisor hypomineralisation: Randomised clinical trial

Abstract

Background: Molar-incisor hypomineralisation (MIH) is a qualitative enamel defect. Aim: To investigate the low-level laser therapy (LLLT) associated with fluoride varnish for the desensitisation of teeth with MIH. Design: A randomised clinical trial was conducted with 66 children, randomly allocated to the treatments: laser (L); fluoride varnish (FV); and laser + fluoride varnish (L + FV). The participants in the L group underwent two sessions of LLLT (48-hour interval). The FV group received four applications of varnish at one-week intervals. The L + FV underwent two sessions of LLLT and four applications of varnish. Prior to each session and one month after the onset of treatment, tooth sensitivity and its magnitude were evaluated. Intra-and inter-group comparisons were performed (α = 5%). Results: A significant reduction in the mean sensitivity score was found over time in all groups. After the final treatment, a significant difference was found between the L and L + FV groups (P = .011), with a lower score in the L + FV group (0.09), whereas no difference was found between the FV and L + FV groups (P = .095). Conclusions: Fluoride varnish and the combination of treatments (L + FV) had greater desensitising action on teeth with MIH. Laser therapy demonstrated an immediate desensitising effect, whereas fluoride varnish had a late-onset effect. K E Y W O R D S child, dentine sensitivity, fluoride, topical, low-level laser light therapy, tooth demineralisation 324 | MUNIZ et al.

New Technologies in Orthodontics: A Digital Workflow to Enhance Treatment Plan and Photobiomodulation to Expedite Clinical Outcomes

“…This spontaneous eruption was expedited by the administration of PBM, which is able to provoke an accelerated metabolic activity by increasing cellular turnover [13], increasing vascular activity [14,33,34], and the availability of ATP [15,35,36]. In this respect, PBM is a free-side effects procedure that has also been validated for several therapeutic applications in children [13,37,38].…”

Guidelines for reporting randomized controlled trials in paediatric dentistry based on the CONSORT statement

“…Example: “A randomised clinical trial was conducted with 66 children and a total of 214 teeth with a sensitivity score ≤3. The study was developed at the paediatric dentistry clinic of educational institution in the city of São Luís, Brazil, between March and December 2018” 26 …”

“…An example of flow chart to exhibit steps involved in the randomized controlled trial (obtained from Muniz et al 26 )…”

“…As each child was included in the study, an envelope of random sequence received the name of the participant. The envelope was opened prior to the treatment to be instituted” 26 …”

“…Example: “This study was supported by the Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão (FAPEMA) (State of Maranhão Foundation for Assistance to Research and Scientific and Technological Development) (Universal # 01060/17)” 26 …”