Efficacy of low carbohydrate diet for type 2 diabetes mellitus management: A systematic review and meta-analysis of randomized controlled trials

Yue, Meng; Bai, Hao; Wang, Shijun; Li, Zhaoping; Wang, Qian; Chen, Liyong

doi:10.1016/j.diabres.2017.07.006

Cited by 170 publications

(170 citation statements)

References 34 publications

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“…Previous systematic review and meta‐analysis reported different dietary carbohydrate proportions in the included studies. Several studies included less restrictive carbohydrate diets (approximately 40% total calorie or less) while others included only VLCKD (approximately 20% total calorie or less) . Current meta‐analysis uses the less restrictive carbohydrate diet in inclusion criteria.…”

Section: Discussionmentioning

confidence: 99%

Effect of low‐carbohydrate diet on markers of renal function in patients with type 2 diabetes: A meta‐analysis

Suyoto

2018

Diabetes Metabolism Res

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Meta-analysis was conducted to clarify the effect of low-carbohydrate diet (LCD) on renal function in patients with type 2 diabetes. An extensive literature search was conducted on scientific databases including PubMed, Scopus, and Cochrane Library until September 2017. Only controlled trials on human subjects written in English were included in this meta-analysis. Several markers of renal function were compared between subjects who adopted an LCD or control diet, including estimated glomerular filtration rate, creatinine clearance, urinary albumin, serum creatinine, and serum uric acid. Random effect model was used in the analysis of each marker. In this meta-analysis, 12 controlled trials were selected, which involved 942 participants (500 received LCD and 442 received a control diet). The pooled standardized mean difference (SMD) of estimated glomerular filtration rate from LCD vs control diet was not different (pooled SMD: 0.26; 95% CI, -0.03 to 0.55; P = .08). Investigation on creatinine clearance also showed no significant difference (pooled SMD: 0.51; 95% CI, -0.38 to 1.40; P = .26). Other comparisons from urinary albumin (pooled SMD: -0.04; 95% CI, -0.75 to 0.67; P = .90), serum creatinine (pooled SMD: -0.57; 95% CI, -1.51 to 0.38; P = .24), and serum uric acid (pooled SMD: -0.86; 95% CI, -4.00 to 2.28; P = .59) also showed no significant difference in the results. In the present meta-analysis, no effect on markers of renal function was found after provision of a LCD compared with a control diet in patients with type 2 diabetes.

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Section: Discussionmentioning

confidence: 99%

Effect of low‐carbohydrate diet on markers of renal function in patients with type 2 diabetes: A meta‐analysis

Suyoto

2018

Diabetes Metabolism Res

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“…A meta-analysis published in Diabetes Research and Clinical Practice in July 20178 found “a beneficial effect of low carb intervention on glucose control in patients with type 2 diabetes,” with a further “positive effect on triglycerides and HDL [high density lipoprotein] cholesterol.”…”

Section: Evidence Lackingmentioning

confidence: 99%

Low calorie and low carb diets for weight loss in primary care

Feinmann¹

2018

BMJ

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“…Atkins and Bernstein have originally begun LCD, which had been an new idea at that time [1,2]. After that, the efficacy of LCD has been known and reported in Western countries [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%