2012
DOI: 10.1590/s1517-83822012000400017
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Abstract: By using agar well diffusion assay, antifungal activity of aqueous extract prepared from Egyptian garlic (Allium sativum L.) was evaluated in vitro against two strains of Aspergillus flavus (OC1 and OC10) causing human ocular infection. The recorded minimum inhibitory concentration (MIC) for growth inhibition of both strains was 3.60 mg/ml. Aqueous garlic extract (AGE) was used in successive in vivo tests as an attempt to cure rabbit's fungal keratitis caused by A. flavus OC1. Findings showed that diluted prep… Show more

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Cited by 12 publications
(4 citation statements)
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“…Investigations into the use of nanoparticle technology with terbinafine and silver have also shown promising results [189,214]. In addition, topical aqueous garlic extracts have been tested on rabbit keratitis models infected with A. flavus [76]. Nonetheless, fungal keratitis is a complex entity with many considerations when it comes to treatment.…”
Section: Treatmentmentioning
confidence: 99%
“…Investigations into the use of nanoparticle technology with terbinafine and silver have also shown promising results [189,214]. In addition, topical aqueous garlic extracts have been tested on rabbit keratitis models infected with A. flavus [76]. Nonetheless, fungal keratitis is a complex entity with many considerations when it comes to treatment.…”
Section: Treatmentmentioning
confidence: 99%
“…Lactoferricin B and short imidazolium chains have shown anti-biofilm properties and have been studied as a possible component to add to contact lens cleaning solution or as an adjunct to help increase the susceptibility of fungi to anti-fungal agents [69,70]. Even topical aqueous garlic extract has been used in in vivo rabbit models infected with A. flavus [71].…”
Section: Methodsmentioning
confidence: 99%
“…S. pneumoniae, S. aureus, S. pyogenes, H. influenzae and anaerobic bacteria such as Fusobacterium & Peptostreptococcal species are the pathogens most frequently associated with orbital cellulitis. Some cases of orbital cellulitis have been linked to bacteria such Aeromonashydrophila, Pseudomonas aeruginosa, and Eikenellacorrodens [43].…”
Section: Preseptal and Orbital Cellulitismentioning
confidence: 99%