2014
DOI: 10.5935/0004-2749.20140044
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Efficacy of a lutein-based dye (PhacodyneTM) for visualizing anterior capsulorhexis during cataract surgery by phacoemulsification

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Cited by 5 publications
(6 citation statements)
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References 19 publications
(27 reference statements)
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“…This combination was used during cataract surgery by phacoemulsification for screening anterior capsulorhexis in patients. The result of this study indicated that this combined dye might be an alternative for continuous circular capsulorhexis (CCC) in human due to its safe, effective and antioxidant profile [72]. The results of Chew et al's study was contrary to the most studies.…”
Section: Role Of Lutein and Zeaxanthin In Cataractcontrasting
confidence: 56%
“…This combination was used during cataract surgery by phacoemulsification for screening anterior capsulorhexis in patients. The result of this study indicated that this combined dye might be an alternative for continuous circular capsulorhexis (CCC) in human due to its safe, effective and antioxidant profile [72]. The results of Chew et al's study was contrary to the most studies.…”
Section: Role Of Lutein and Zeaxanthin In Cataractcontrasting
confidence: 56%
“…Previous reports had already shown the safety and efficacy of Phacodyne during cataract surgery. 27 Although these results indicate a similar behavior for these two dyes, other studies point to retinal toxicity of TB. Several studies have described retinal damage after exposure to TB in a bovine model, as well as, in vitro rodent neurosensory cells.…”
Section: Discussionmentioning
confidence: 78%
“…[19][20][21] In our previous publications, we have described the use of novel intraocular dyes in which Lutein is the primary component in cataract and vitreoretinal surgeries. [22][23][24][25][26][27][28] These L/Z-based dyes have shown efficacy in staining target membranes such as AC, ILM, and the vitreous, as well as an excellent safety profile. [22][23][24][25][26][27][28] The nature of the interaction of L/Z-based dyes with their target membranes is herein investigated using Langmuir monolayer models simulating the ILM, vitreous, AC, and epiretinal membrane (ERM).…”
mentioning
confidence: 99%
“…Lutein/trypan blue dye was tested as a good, useful, and safe dye during capsulorhexis in phacoemulsification. No signs of toxicity or side effects were detected during follow-up (30 days) [ 10 ]. This protective effect was associated with the properties of lutein, as suggested by clinical, histological, and electroretinographic analyses performed to evaluate the safety profile of solutions containing lutein in rabbit eyes after intravitreal injections, implying good protection of vitreoretinal interphase and underlined retina [ 11 ].…”
Section: Introductionmentioning
confidence: 99%