Efficacy of a glucose meter connected to a mobile app on glycemic control and adherence to self-care tasks in patients with T1DM and LADA: a parallel-group, open-label, clinical treatment trial

Abstract

Objective: The main aim of the study was to evaluate the patients' glycemic control and adherence to self-care tasks. Materials and methods: Patients with type 1 diabetes mellitus (T1DM) or latent autoimmune diabetes of the adult (LADA) using a multiple daily injection (MDI) regimen with carbohydrate counting (n = 25, Subgroup B) or fixed insulin dose (n = 25, Subgroup C) were allocated to use the application (app) for 12 weeks. Both subgroups were compared with each other and against a control group (n = 25, Group A) comprising patients with T1DM or LADA treated with continuous subcutaneous insulin infusion (CSII) in a parallel-group, open-label, clinical treatment trial. All patients had glycated hemoglobin (A1C) levels measured and were asked to fill out the Diabetes Self-Management Profile (DSMP) questionnaire at study start and end. The patients were instructed to measure capillary glucose six times daily in study weeks 4, 8, and 12. Results: Mean A1C levels decreased 0.725% in Subgroup C in intragroup analysis (p = 0.0063), and had a mean variation of 0.834% compared with Group A (p = 0.003). Mean DSMP scores increased 5.77 points in Subgroup B in intragroup analysis (p = 0.0004) and increased by a mean of 6.815 points in relation to Group A (p = 0.002). Conclusion: OneTouch Reveal improved both A1C levels and DSMP scores in patients with T1DM or LADA compared with standard treatment (CSII).

Characteristics of carbohydrate counting practice associated with adequacy of glycated hemoglobin in adults with type 1 diabetes mellitus in Brazil

“…As for the use of apps and the food scale, using specific and non-specific CC apps and using the food scale to do the CC, when eating something different than usual and to make culinary recipes was associated with having adequate HbA1c in this study. Using mobile apps and food scales helps to perform CC more accurately and frequently, optimizing glycemic control and reducing counting errors ( 49 – 51 ). In the cross-sectional study by Trawley et al.…”

Comparison of three insulin bolus calculators to increase time in range of glycemia in a group of poorly controlled adults Type 1 diabetes in a Brazilian public health service

“…This systematic review and meta-analysis of efficacy of mobile APPs to support care of people with diabetes, confirmed that A1c could be improved when it strengthens the perception of self-care and allow remote access to health care professional, but an important characteristic measured in these studies was participants education degree and the ability in adopting new technologies [ 25 ]. In addition, a recent Brazilian study carried out with a group of adults with T1D or latent autoimmune diabetes of adult (LADA), undergoing treatment with MDI plus carbohydrate counts or MDI plus fixed doses of insulin compared to CSII also observed that using SMBG device connected to a cell phone application contributed to better glycemic control and increased adherence to tasks of self-care [ 26 ].…”

Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocol

“…While some apps are designed for the general population and may present challenges for those with health conditions, there are also apps that are specifically helpful for managing certain conditions like T1DM. For instance, diabetes apps have shown benefits for glycemic control ( 20 ), reducing HbA1c ( 21 ), and improving health-related quality of life (HRQL) ( 22 ).…”