Efficacy and Safety of Single-Dose Zoledronic Acid for Osteoporosis in Frail Elderly Women

Treatment of Osteoporosis in Australian Residential Aged Care Facilities: Update on Consensus Recommendations for Fracture Prevention

“…61 A more recent study by the same author tested the safety and efficacy of single-dose zoledronic acid for osteoporosis in a population of nursing home residents. 62 There was no difference in terms of the incidence of fractures between the treatment and placebo groups. However, the power of the study was limited by the small sample size and by the significant differences between both groups in terms of comorbidities.…”

A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement

“…Relative risk reductions of spine and non-vertebral fractures by TABM in subjects with bone densitometry-diagnosed osteoporosis are 40-60 and 20-40 %, respectively [14,61]. Number needed to treat (NNT) to prevent a fracture is lower in people at high risk of fractures, especially in those with prior fragility fractures [13,37,[61][62][63][64][65][66][67][68][69][70][71][72][73].…”

A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement

“…Relative risk reductions of spine and non-vertebral fractures by TABM in subjects with bone densitometry diagnosed osteoporosis are 40-60% and 20-40%, respectively (14,61). Number-Needed-to-Treat (NNT) to prevent a fracture is lower in people at high risk of fractures, and especially in those with prior fragility fractures (13,37,(61)(62)(63)(64)(65)(66)(67)(68)(69)(70)(71)(72)(73).…”