Efficacy and Safety of Limbal-Conjunctival Autografting with Limbal Fixation Sutures after Pterygium Excision

Abstract

Purpose: To evaluate the efficacy and safety of limbal-conjunctival autografting with limbal fixation sutures after pterygium excision. Methods: We retrospectively reviewed the records of 90 patients (103 eyes) who received limbal-conjunctival autografts with limbal fixation sutures after excision of the primary pterygium (82 eyes) and recurrent pterygium (21 eyes). Results: The study subjects comprised 41 male patients (47 eyes) and 49 female patients (56 eyes) with a mean age of 51.1 ± 10.5 years (range 32–77). The mean follow-up period was 18.9 ± 9.2 months (range 12–50). Among the 103 eyes, recurrence occurred in 2 eyes (1.9%) after 2 and 4 months, respectively. As complications, 1 case of conjunctival cyst and 2 cases of pseudopterygium at the donor site were reported. Conclusions: Limbal-conjunctival autografting with limbal fixation sutures appears to be an effective and safe method of reducing the recurrence rate after pterygium excision.

Pterygium Recurrence, Astigmatism and Visual Acuity following Bare-Sclera Excision and Conjunctival Autograft with or without Additional Phototherapeutic Keratectomy

“…Furthermore, as for the use of amniotic membrane as an alternative to CAGs, Küçükerdönmez et al [12] did not yield any significant difference in recurrence rates in a prospective randomized clinical trial of 78 patients, and both Tananuvat and Martin [13 ]and Liang et al [14] demonstrated lower recurrent rates while using CAGs. With CAGs including the limbal areas, Han et al [15] and Torres et al [16] reported recurrence rates of 1.9 and 7.9%, respectively.…”

Pseudopterygium: An Algorithm Approach Based on the Current Evidence

“…Conjunctival and limbal-conjunctival grafts are described causes of pseudopterygium at the donor site [ 70 ]. Nevertheless, the incidence is low as reported in the literature as a result of the low amount of tissue that is necessary to be taken from the donor eye [ 71 ]. Han et al [ 71 ] studied the efficacy and safety limbal-conjunctival autografting with limbal fixation sutures after pterygium.…”

“…Nevertheless, the incidence is low as reported in the literature as a result of the low amount of tissue that is necessary to be taken from the donor eye [ 71 ]. Han et al [ 71 ] studied the efficacy and safety limbal-conjunctival autografting with limbal fixation sutures after pterygium. A total of 90 patients with pterygium and recurrent pterygium were treated with this technique.…”

Efficacy of Subconjunctival Bevacizumab Injection after Pterygium Excision with Limbal Conjunctival Autograft in Recurred Pterygium

“…12 외국의 연구에서 도 익상편 제거수술 후 자가 결막 및 윤부이식술 등의 수술 기법의 발달과 함께 익상편의 재발률이 3-17%로 감소하였 으나, 20 재발익상편의 경우 결막자가이식술을 시행한 경우 에도 재발률이 31-33%에 달하는 것으로 보고되고 있다. 21 Bianchi et al 22 은 익상편 조직의 면역화학염색을 통해 원 발익상편의 상피, 혈관내피 및 실질조직에서 혈관내피성장 인자(vascular endothelial growth factor; VEGF)의 발현이 정상 결막조직에 비해 증가하였음을 보고하였는데, 이는 VEGF가 혈관형성(angiogenesis)을 촉진하여 익상편의 증 식을 촉진할 수 있음을 시사한다.…”