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Cited by 122 publications
(131 citation statements)
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“…It is of particular value in patients with high solute transport (14), and several randomized trials have demonstrated better ultrafiltration compared with 2.27% glucose (15)(16)(17). A recent open study in APD patients, where icodextrin was used in the daytime dwell compared with 2.27% glucose, demonstrated clinically important changes in fluid content and BP control (18).…”
mentioning
confidence: 99%
“…It is of particular value in patients with high solute transport (14), and several randomized trials have demonstrated better ultrafiltration compared with 2.27% glucose (15)(16)(17). A recent open study in APD patients, where icodextrin was used in the daytime dwell compared with 2.27% glucose, demonstrated clinically important changes in fluid content and BP control (18).…”
mentioning
confidence: 99%
“…Namely, it is not uncommon for fast transport patients using glucose-based solutions to complete the long day dwell with zero or negative net fluid removal (10)(11)(12), and hence, sodium removal. Such fast transport patients with high D/P creatinine were reported to have lower convective sodium mass transport associated with reduced transcapillary ultrafiltration, while demonstrating significantly greater convective sodium APD = automated peritoneal dialysis; CAPD = continuous ambulatory peritoneal dialysis; UF = ultrafiltration; NaR = sodium removed; CHO = carbohydrate absorbed; N = number of exchanges; H = high; HA = high-average; LA = low-average; L = low.…”
Section: Discussionmentioning
confidence: 99%
“…As a result, it was not possible to elaborate on the role that icodextrin may have played in the demonstrated survival advantage and any potential improvements in fluid and solute removal. Early studies of icodextrin as a long dwell PD solution evaluated its metabolism, safety profile, and dialysis adequacy relative to glucose-based PD solutions (10)(11)(12)(13). In several studies, sodium removal with icodextrin was reported only for the study population as a whole (14)(15)(16)(17) and the dependence of UF on patient transport characteristics was discussed in a limited number of cases (18,19).…”
mentioning
confidence: 99%
“…Calculation of dialysate osmolality was based on the concentrations of solutes present (glucose, sodium, calcium, magnesium, chloride, lactate, bicarbonate, urea, and creatinine). At the start of the dwell, osmolality varied as a function of infused solution volume (osmolality, o I : 483 mOsmol/L for 3.86% glucose) and V R (osmolality, o VR : assumed equal to plasma osmolality, 300 mOsmol/L) as shown in the equation [3] where o D0 is the dialysate osmolality immediately after infusion.…”
Section: Methodsmentioning
confidence: 99%