Effects on secretory IgA levels in small intestine of mice that underwent moderate exercise training followed by a bout of strenuous swimming exercise

Exercise, fitness, and the gut

“…Whether this systemic anti-inflammatory effect of muscle contraction is reflected at the level of the intestinal immune system is unknown but seems likely. Few studies have been conducted in humans with most data based on experimental animals [56,57]. Similarly, because of a lack of prospective trials, it is unclear whether increasing physical activity in the premorbid period confers a reduced risk of developing conditions such as IBD.…”

Annexin A2 mediates collagen VI secretion, pulmonary elasticity, and bronchial epithelial cell apoptosis

“…After swimming, mice were placed in cages containing normal bedding and maintained at 21˚C. AnxA2 2/2 and AnxA2 +/+ littermate mice underwent a 3 week training period consisting of supervised swim sessions 4-5 times per week and increasing in duration by 10 minute intervals to a plateau of 90 minutes per session (Godínez-Victoria et al, 2012;Kregel et al, 2006). Thereafter, mice were subjected to 90 minute daily swim sessions over a 3 week period.…”

Intermittent fasting modulates IgA levels in the small intestine under intense stress: A mouse model

“…Specific oligonucleotide primers were originally generated by using the online assay design software ProbeFinder (http://www.universal-probelibrary.com), as previously reported (Godinez-Victoria et al, 2012). The mRNA levels were calculated by using the comparative parameter threshold cycle (Ct) method and normalized to ribosomal RNA.…”