2018
DOI: 10.1007/s00726-018-2643-2
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: The effects of β-alanine (BA) and sodium bicarbonate (SB) on energy metabolism during work-matched high-intensity exercise and cycling time-trial performance were examined in 71 male cyclists. They were randomised to receive BA + placebo (BA, n = 18), placebo + SB (SB, n = 17), BA + SB (BASB, n = 19), or placebo + placebo (PLA, n = 18). BA was supplemented for 28 days (6.4 g day) and SB (0.3 g kg) ingested 60 min before exercise on the post-supplementation trial. Dextrose and calcium carbonate were placebos fo… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

7
20
0

Year Published

2019
2019
2023
2023

Publication Types

Select...
5
1

Relationship

1
5

Authors

Journals

citations
Cited by 26 publications
(27 citation statements)
references
References 44 publications
7
20
0
Order By: Relevance
“…Moderate, albeit non-significant, increases were observed for W [LA] during the HICT without altering energy demand or contribution from W AER , which is in agreement to findings from recent studies (20,21,31). Despite not achieving statistical significance, these increases were considered substantial for both SBC2 (+15.8%) and SBC3 (+30.3%) when compared to PLA, with the relatively small absolute changes in W [LA] attributed to the controlled total mechanical work during the HICT (20). The most novel finding, however, was that there may be a dose-response effect of NaHCO 3 ingestion on changes in energy system contributions, with a small effect size present for W [LA] in favor of SBC3.…”
Section: Discussionsupporting
confidence: 92%
See 4 more Smart Citations
“…Moderate, albeit non-significant, increases were observed for W [LA] during the HICT without altering energy demand or contribution from W AER , which is in agreement to findings from recent studies (20,21,31). Despite not achieving statistical significance, these increases were considered substantial for both SBC2 (+15.8%) and SBC3 (+30.3%) when compared to PLA, with the relatively small absolute changes in W [LA] attributed to the controlled total mechanical work during the HICT (20). The most novel finding, however, was that there may be a dose-response effect of NaHCO 3 ingestion on changes in energy system contributions, with a small effect size present for W [LA] in favor of SBC3.…”
Section: Discussionsupporting
confidence: 92%
“…Considering that enhanced buffering capacity is responsible for elevating glycolytic contribution, one explanation for these dose-dependent results could relate to the total amount of H + that can be neutralized. Assuming that total blood volume is ~5 L and that [ ] was as small as ~1.0 mmol.l −1 higher for SBC3 vs. SBC2, then the higher dose could have allowed the neutralization of an extra ~5 mmoles of H + (based on the 1:1 stoichiometry of and H + reaction), in theory eliciting a greater up-regulation of glycolytic contribution ( 20 ). It is important to note, however, that as the current methodology only indirectly assesses glycolytic flux (i.e., from changes in [BLa − ]), these increases in W [LA] contribution may overestimate glycolytic activation, instead reflecting greater lactate efflux from working muscles ( 5 ).…”
Section: Discussionmentioning
confidence: 99%
See 3 more Smart Citations