Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat

Brun, L.R.; Brance, María Lorena; Lombarte, Mercedes; Maher, María Cielo; Loreto, Veronica Di; Rigalli, Alfredo

doi:10.1007/s00223-015-0043-0

Cited by 18 publications

(13 citation statements)

References 44 publications

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“…Therefore, we speculated that it might not be sufficient to modify these markers. Experimental studies also have found no evidence of bone parameters modification with the yerba mate consumption (Brun et al, ).…”

Section: Discussionmentioning

confidence: 99%

The yerba mate intake has a neutral effect on bone: A case–control study in postmenopausal women

Veiga

Bringhenti

Bolignon

et al. 2017

Phytotherapy Research

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Nutritional factors have been associated with osteoporosis and fractures. The intake of coffee may increase the risk of fracture whereas the intake of black and green tea is associated with its reduction. Recently, consumption of yerba mate was associated with increased bone mineral density in postmenopausal women. Nonetheless, its influence on fracture is not known. The aim of this study was to evaluate the effect of yerba mate tea intake on fractures, bone markers, calcium homeostasis, and oxidative stress in postmenopausal women. A case-control study was carried out in South Brazil, 46 women with fractures and 49 controls completed the study. There was no significant difference between the frequency of fractures in women who drank mate tea and women who did not (48.3% vs. 48.5%, p = .99). Moreover, there was no significant difference concerning the serum levels of total calcium, phosphorus, PTH, vitamin D, P1NP, and CTX in the subjects with the history of yerba mate use when compared to controls. Higher serum levels of NOx were found in women who drank the yerba mate infusion. In conclusion, the yerba mate intake is not associated with fracture, and it appears to have a neutral effect on the bone metabolism.

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Section: Discussionmentioning

confidence: 99%

The yerba mate intake has a neutral effect on bone: A case–control study in postmenopausal women

Veiga

Bringhenti

Bolignon

et al. 2017

Phytotherapy Research

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“…Bone mineral density (BMD, mg Ca/cm 2 ) was determined on left tibias using X-ray absorption measurement (Work Ray 70 kV, Workman SRL, Argentina) simultaneously with an aluminum step wedge, which was previously calibrated with known Ca concentrations [19]. The BMD was determined at the same anatomical location later used for histo-morphometric measurements with Image J 1.48 software.…”

Section: Methodsmentioning

confidence: 99%

“…The following parameters were measured (ImageJ 1.48 software): total number of nodes (Nd), number of node-to-node branches (NNd), number of node-to-termini branches (NNdTm), number of trees ( T ), number of terminals (Tm), and number of branches with two terminals (NTm). With these parameters, we calculated the interconnectivity parameters: interconnectivity index [ICI = Nd × NNd)/ T × (NNdTm + 1)]; node-to-termini ratio [R = Nd/Tm]; mean size of branches [Dist (mm) = ∑ branches size/(NNdTm + NNd + NTm)]; and the new interconnectivity index [NDX (%/mm) = (R × NNd × (BV/TV) × Tb.Th)/((NTm + NNdTm) × Dist × Tb.Sp)] [19, 21]. The higher ICI, R and NDX and the lower NTm indicates more connectivity among trabeculas.…”

Section: Methodsmentioning

confidence: 99%

Increased calcium uptake and improved trabecular bone properties in intestinal alkaline phosphatase knockout mice

et al. 2017

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Previous studies have demonstrated a negative correlation between intestinal alkaline phosphatase (IAP) activity and calcium (Ca) absorption in the gut, as IAP acts as a protective mechanism inhibiting high Ca entry into enterocytes, preventing Ca overload. Here we evaluated Ca absorption and bone properties in knockout mice (KO) completely devoid of duodenal IAP (Akp3 mice). Female C57BL/6 control mice (WT, n = 7) and KO mice (n = 10) were used to determine Ca absorption in vivo and by in situ isolated duodenal loops followed by histomorphometric analysis of duodenal villi and crypts. Bone mineral density, morphometry, histomorphometry and trabecular connectivity and biomechanical properties were measured on bones. We observed mild atrophy of the villi with lower absorption surface and a significantly higher Ca uptake in KO mice. While no changes were seen in cortical bone, we found better trabecular connectivity and biomechanical properties in the femurs of KO mice compared to WT mice. Our data indicate that IAP KO mice display higher intestinal Ca uptake, which over time appears to correlate with a positive effect on the biomechanical properties of trabecular bone.

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“…Main bioactive compounds found in Yerba Mate and their health benefits [8].DCQ -Dicaffeoylquinic acid them energy, while at the same time, not causing nervousness which sometimes occurs after the consumption of coffee [32]. In addition, research carried out on rats demonstrated that Yerba Mate is safe for bone health, despite the high content of caffeine that has a negative impact on bone mineral density [33]. However, it should be remembered that an excessive amount of caffeine may cause headache, migraine and high blood pressure in some people, especially in pregnant women, who should limit its consumption due to the risk of miscarriage and low birth weight of a baby [32].…”

Section: Introductionmentioning

confidence: 99%

Health properties of Yerba Mate

Lutomski¹,

Goździewska²,

Florek-Łuszczki³

2020

Ann Agric Environ Med.

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Introduction. Yerba Mate, also called Paraguay tea, is obtained from the dried leaves (approximately 95%) and stems (about 5%) of the evergreen shrub-tree Ilex paraguariensis. Each year, the consumption of yerba mate becomes increasingly popular in North America and Europe. The fashion for Paraguay tea has also reached Poland. During the period 2012-2018, as much as an 8-fold increase has been observed in the import of this raw material to our country. Objective. The aim of the study is analysis of the present state of knowledge concerning the health effects of Yerba Mate, based on selected scientific literature. Dicussion. The consumption of yerba mate may exert a beneficial effect on human health and its consumption is recommended in the treatment of obesity and while practicing sports. Nevertheless, it should be remembered that a very high consumption of the tea, especially when very hot, may increase the risk of occurrence of cancer, which has not been unequivocally confirmed by scientific studies to-date. Conclusions. It has been confirmed that this beverage shows a number of beneficial health effects, including: a protective effect on liver cells, stimulation of the central nervous system, anti-inflammatory effect, as well as a positive effect on the cardiovascular system.

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Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat

Cited by 18 publications

References 44 publications

The yerba mate intake has a neutral effect on bone: A case–control study in postmenopausal women

The yerba mate intake has a neutral effect on bone: A case–control study in postmenopausal women

Increased calcium uptake and improved trabecular bone properties in intestinal alkaline phosphatase knockout mice

Health properties of Yerba Mate

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