Effects of UVB and UVC irradiation on cariogenic bacteria in vitro

Uchinuma, Shigeki; Shimada, Yasushi; Matin, Khairul; Hosaka, Keiichi; Yoshiyama, Masahiro; Sumi, Yasunori; Tagami, Junji

doi:10.1007/s10103-018-2685-4

Cited by 8 publications

(5 citation statements)

References 38 publications

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“…The SLR's results demonstrate a concentration of studies [3,8,17,[21][22][23][28][29][30][31][32][33][34][35][36][37][38][39][40] in this scientific field. Of these studies, all found some level of decontamination effectiveness.…”

Section: Human Healthmentioning

confidence: 76%

“…Of these studies, all found some level of decontamination effectiveness. In terms of disinfection (at least three log-reduction), we have seven studies [3,24,[33][34][35][36][37][38] indicating it. Meanwhile, ten studies [8,17,21,23,[28][29][30][31][32]39] indicate elimination of biological indicators (sterilization) or growth inhibition.…”

Section: Human Healthmentioning

confidence: 99%

“…All the studies in our SLR found some decontamination levels emerging from UVC LEDs. Some reached disinfection levels [2,[5][6][7]10,11,18,26,[34][35][36]45,49,52,53,[56][57][58][60][61][62][63]67,69,71], while a few achieved sterilization or untraceable levels [1, [28][29][30]37,46,51,54,59,68].…”

Section: Bacteriamentioning

confidence: 99%

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A Comprehensive Analysis of the UVC LEDs’ Applications and Decontamination Capability

et al. 2022

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The application of light-emitting diodes (LEDs) has been gaining popularity over the last decades. LEDs have advantages compared to traditional light sources in terms of lifecycle, robustness, compactness, flexibility, and the absence of non-hazardous material. Combining these advantages with the possibility of emitting Ultraviolet C (UVC) makes LEDs serious candidates for light sources in decontamination systems. Nevertheless, it is unclear if they present better decontamination effectiveness than traditional mercury vapor lamps. Hence, this research uses a systematic literature review (SLR) to enlighten three aspects: (1) UVC LEDs’ application according to the field, (2) UVC LEDs’ application in terms of different biological indicators, and (3) the decontamination effectiveness of UVC LEDs in comparison to conventional lamps. UVC LEDs have spread across multiple areas, ranging from health applications to wastewater or food decontamination. The UVC LEDs’ decontamination effectiveness is as good as mercury vapor lamps. In some cases, LEDs even provide better results than conventional mercury vapor lamps. However, the increase in the targets’ complexity (e.g., multilayers or thicker individual layers) may reduce the UVC decontamination efficacy. Therefore, UVC LEDs still require considerable optimization. These findings are stimulating for developing industrial or final users’ applications.

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Section: Human Healthmentioning

confidence: 76%

Section: Human Healthmentioning

confidence: 99%

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A Comprehensive Analysis of the UVC LEDs’ Applications and Decontamination Capability

et al. 2022

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“…Because most lizards benefit from full‐spectrum lighting, including UVA/UVB light, light bulbs are usually installed in their cages (Varga, 2004). UVA/UVB are longer wavelengths than UVC, but they possess cytotoxic and bactericidal effects (Fluhr & Gloor, 1997; Hockberger, 2002; Uchinuma et al., 2019). The phage was stable under UVA/UVB light for 1 hr (Figure 4c).…”

Section: Discussionmentioning

confidence: 99%

Bacteriophage as an alternative to prevent reptile‐associated Salmonella transmission

Kwon

Kim

et al. 2021

Zoonoses and Public Health

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Salmonellosis is a major global public health issue; its most common infection, gastroenteritis, accounts for approximately 90 million illnesses and 150,000 mortalities per year. Eradicating salmonellosis requires surveillance, prevention and treatment, entailing large expenditures. However, it is difficult to control Salmonella transmission because it occurs via multiple routes; exotic reptiles are a reservoir of Salmonella and comprise one such route. As the popularity of exotic pets and animal exhibition has increased, human encounters with reptiles have also increased. As a result, reptile‐associated salmonellosis (RAS) has been recognized as an emerging disease. The development of antimicrobial resistance in RAS‐causing Salmonella sp. requires alternatives to antibiotics. In this study, bacteriophages have been established as an alternative to antibiotics because only target bacteria are lysed; thus, they are promising biocontrol agents. Here, bacteriophage pSal‐SNUABM‐02, which infects and lyses reptile Salmonella isolates, was isolated and characterized. The morphology, host range, growth traits and stability of the phage were investigated. The phage was assigned to Myoviridae and was stable in the following conditions: pH 5–9, 4–37°C, and ultravioletA/ultravioletB (UVA/UVB) exposure. Salmonella clearance efficacy was tested using planktonic cell lysis activity and biofilm degradation on polystyrene 96‐well plates and reptile skin fragments. The phage exhibited vigorous lysis activity against planktonic cells. In in vitro biofilm degradation tests on reptile skin and polystyrene plates, both low‐ and high‐concentration phage treatments lowered bacterial cell viability by approximately 2.5–3 log colony‐forming units and also decreased biomass. Thus, bacteriophages are a promising alternative to antibiotics for the prevention and eradication of RAS.

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“…Thus, the shifting toward new technologies for preventing dental caries is very prominent. Previous studies have evaluated the effectiveness of using ultraviolet light (UVL) irradiation on reducing the cariogenicity of some bacteria that cause dental caries [ 12 – 14 ]. This photodynamic technology in preventing dental caries was used first by Downes and Blunt in 1877 [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of bactericidal effects of ultraviolet light C irradiation on cariogenic bacteria: An in vitro study

2021

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Backgrounds Ultraviolet light C (UVL-C) irradiation has demonstrated an antimicrobial action against various pathogens. This study aimed to evaluate the bactericidal effect of UVL-C irradiation against cariogenic oral bacteria (Streptococcus mutans) in single layers and colonies grown on solid surfaces. Methods Two different experiments were performed. In the first experiment, a single layer of Streptococcus mutans bacteria on agar plates was exposed to UVL-C irradiation at energies from 0 to 21 mWs/cm2. The second experiment was conducted to inhibit viability of bacterial colonies on solid surfaces. The samples were derived from saliva from a patient where bacteria were grown on plastic strips and then exposed to UVL-C. The highest energy was 1050 mWs/cm2. Results Exposure to 21 mWs/cm2 was bactericidal in single layers of Streptococcus mutans. The result for bacterial colonies on solid surfaces indicated only a bacteriostatic effect, even at energies of 1050 mWs/cm2. Conclusions Ultraviolet light C exhibits bactericidal effects on single layers of Streptococcus mutans but has a limited effect on bacterial colonies in a biofilm. It is a matter of debate whether these in vitro results would have the same effect in clinical setting.

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Effects of UVB and UVC irradiation on cariogenic bacteria in vitro

Cited by 8 publications

References 38 publications

A Comprehensive Analysis of the UVC LEDs’ Applications and Decontamination Capability

A Comprehensive Analysis of the UVC LEDs’ Applications and Decontamination Capability

Bacteriophage as an alternative to prevent reptile‐associated Salmonella transmission

Evaluation of bactericidal effects of ultraviolet light C irradiation on cariogenic bacteria: An in vitro study

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