Effects of tetracycline on the secondary metabolites and nutritional value of oilseed rape (Brassica napus L.)

Abstract

Secondary metabolism, which helps a plant cope with external stress, is sensitive to environmental changes and plays a prominent role in maintaining plant health. However, few studies of the effects of tetracycline on the relationships between secondary metabolism and plant stress responses have been performed. Here, secondary metabolism, nutritional value, and oxidative stress responses in oilseed rape (Brassica napus L.) exposed to tetracycline for 14 d were investigated. Tetracycline inhibited growth and biomass accumulation and decreased the chlorophyll content. The sinapine, phenol, and avonoid contents were 118.46%, 99.67%, and 93.07% higher, respectively, but the carotenoid content was 76.47% lower in plants exposed to 8 mg/L tetracycline than the control plants. Tetracycline affected the nutritional value of oilseed rape. Tetracycline decreased the dietary ber,soluble sugar contents, and microelement (Fe, Mn, and Zn) contents. The antioxidant system alsoresponded strongly to tetracycline. The catalase and peroxidase activities were increased and the superoxide dismutase activity was decreased by tetracycline. Tetracycline caused oxidative damage and secondary metabolite disturbances and adversely affected oilseed rape growth and quality.The results provide a new perspective on the effects of tetracycline on plants in relation to secondary metabolites and improve our understanding involved in the toxicity of tetracycline.

Effects of antibiotics on secondary metabolism and oxidative stress in oilseed rape seeds

“…Excessive reactive oxygen species (ROS) are produced during the growth of oilseed rape seedlings under antibiotic exposure (Zhao et al, 2023), and aerobic metabolism and pollution stress during seed development and formation also produce harmful ROS (Bailly, 2004). There were changes in the relative content of ROS in oilseed rape seeds with TC and SMZ, as shown in Figs.…”

“…Rapeseed is rich in secondary metabolites such as avonoids, carotenoids and tocopherols, which promote human health, and also improve the quality of rapeseed and prolong its storage period (Shen et al, 2023). Recent studies have demonstrated that stresses from antibiotic and heavy metal pollution have signi cant effects on secondary metabolism and antioxidant effects in hydroponically grown rapeseed seedlings (Zhao et al, 2023, Skhawat et al, 2018, but little is known about the effects of antibiotic exposure throughout the growth cycle on rapeseed seed quality and oxidative stress have not been reported.…”

Recent Updates on the Antimicrobial Compounds from Marine‐Derived Penicillium fungi

“…[50,51,52,53,54] Polyketides include a series of natural products with complex structure, such as macrolides, polyenes, anthraquinones, naphthalene, flavonoids, tetracycline and so on. [55,56,57,58] Due to the great application value of these compounds in antimicrobial, anti-tumor, anti-infection, etc., researchers are attracted to carry out in-depth and systematic research on polyketides. The antimicrobial activities of polyketides from marine Penicillium spp.…”

Identification of a BAHD Acyltransferase Gene Involved in Plant Growth and Secondary Metabolism in Tea Plants

“…The leaf growth and the characteristics of secondary metabolites are critically significant for the quality control and production of plants [ 1 ]. Secondary metabolism assists a plant to cope with environmental factors, is sensitive to external changes, and performs a vital role in sustaining plant growth [ 2 ]. In addition, these also can promote plant growth due to preventing the disease by redeeming vegetative growth by the increase of root and shoot systems production [ 3 ].…”