1983
DOI: 10.1016/0016-6480(83)90141-7
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Effects of temperature and dose level on in vivo dynamics of unlabelled bovine insulin in eels (Anguilla anguilla L.)

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“…Thus even though the basis of this response in fish remains to be elucidated, the increase in the level of glycogenolytic hormones (adrenaline or glucagon) as a result of the insulin-induced hypoglycaemia (Matty and Lone, 1985) seems to be the more logical explanation. Our results show that under physiological insulin treatment most of the results obtained in other studies with pharmacological doses are not observed, probably due to a saturation of the system under high insulin levels (Ince, 1983a) which may mask the counter-regulatory natural response to hypoglycaemia by the trout.…”
Section: Acute Insulin Administration: Metabolic Regulation In Muscle
mentioning
confidence: 51%
“…Studies employing physiological doses of insulin are scarce (Capilla et al, 2002;Ince, 1983a;Ince and Thorpe, 1976), and as far as we are aware, in only one of these was the plasma insulin level measured after exogenous administration (Pérez-Sánchez, 1988). On the other hand, almost all the studies carried out to date have focused on acute insulin effects, subjecting fish to transient levels of the hormone, and only a few involved chronic trials (Ablett et al, 1981;Polakof et al, 2008a;Slagter et al, 2005).…”
Section: Introduction
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confidence: 99%
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