Effects of surface treatment of Ti–6Al–4V titanium alloy on biocompatibility in cultured human umbilical vein endothelial cells

Bruni, Sara; Martinesi, Maria; Stio, Maria; Treves, Cristina; Bacci, T.; Borgioli, Francesca

doi:10.1016/j.actbio.2004.11.001

Cited by 85 publications

(35 citation statements)

References 49 publications

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“…4,5 It is used mostly for dental and orthopedic implants. Commercially pure titanium does not have a tensile strength as high as some other implant materials, such as cobalt-chromium.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Anatase Phase on Calcinated Titanium-V Alloy

Hamilton¹,

Butt²,

Patel³

et al. 2013

J Undergrad Research UIC

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Surface modification of titanium implants has been a large focus of recent research. Thermal oxidation is a technique used to diffuse oxygen into the surface of a material to form an oxide layer. By varying the temperature of thermal oxidation, the crystal structure of the TiO2 layer can be changed from anatase to rutile in the range 300 to 600 °C. The crystal structure of anatase has been shown to resemble hydroxyapatite, a mineral that is involved in bone growth. FTIR, an Ellipsometer, and a Geoniometer are used to analyse the anatase concentrations created at 24, 300, 375, and 450 °C. It was found that hydrophilicity increases on rough samples as oxidation temperature increases. Also, a peak shift from anatase to rutile is seen as annealing temperatures increase in the range of 300 to 600 °C. Greater relative anatase formation is seen at 300 and 375 °C. The shift to rutile begins to occur at 450 °C and continues to 600 °C.

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“…4,5 It is used mostly for dental and orthopedic implants. Commercially pure titanium does not have a tensile strength as high as some other implant materials, such as cobalt-chromium.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Anatase Phase on Calcinated Titanium-V Alloy

Hamilton¹,

Butt²,

Patel³

et al. 2013

J Undergrad Research UIC

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“…The addition of alloying elements to titanium (e.g., Al and V) improves titanium's mechanical properties. However, it is possible for the ions to be released and to have a toxic effect on the human organism; thus, it is important to avoid such elements [1][2][3][4][5][6]. These elements can be replaced by nontoxic elements, such as Zr, Nb, Ta, or Mo [5], although the mechanical and microstructural properties of the alloys change due to this replacement.…”

Section: Introductionmentioning

confidence: 99%

Modification of a Ti–Mo alloy surface via plasma electrolytic oxidation in a solution containing calcium and phosphorus

Simka

Krząkała

Korotin

et al. 2013

Electrochimica Acta

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a b s t r a c tInvestigations into the surface modification of a Ti-15Mo alloy via plasma electrolytic oxidation are reported. The oxidation process was conducted in a solution containing Ca(H 2 PO 2 ) 2 , H 3 PO 4 , or (HCOO) 2 Ca. Anodisation was performed at voltages in the range of 100-400 V. The morphology of the sample surface did not change during alloy oxidation at lower voltages. Higher voltages led to the incorporation of calcium and phosphorus or of calcium only into the formed oxide layer and to significant modification of the surface morphology. Based on the SEM and EDX analysis results, a set of samples was selected for further investigations. To study the surface of the Ti-Mo alloy after anodic oxidation, we used scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), thin-layer X-ray diffraction (TL-XRD), and X-ray photoelectron spectroscopy (XPS). The electrochemical characteristics of the modified alloy in Ringer's solution were determined. Anodisation results in a considerable increase in the corrosion resistance of the Ti-15Mo alloy.

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“…1) Titanium metal has recently been used in dental implants, 2) artificial joints, 3) and artificial bones. 4) One of the applications of titanium metal for biomedical parts is bone.…”

Section: Introductionmentioning

confidence: 99%